What is the definition of Familial Prostate Cancer?

Familial prostate cancer is a cluster of prostate cancer within a family. Most cases of prostate cancer occur sporadically in people with no family history of the condition. However, approximately 5% to 10% of prostate cancer cases are believed to be primarily caused by a genetic predisposition to the condition. In many families, the underlying genetic cause is unknown; however, some of these cases are caused by changes (mutations) in the BRCA1, BRCA2, HOXB13, or several other genes. Other cases are likely due to a combination of gene(s) and other shared factors such as environment and lifestyle. High-risk cancer screening at an earlier age is typically recommended in men who have an increased risk for prostate cancer based on personal and/or family histories.

What are the alternative names for Familial Prostate Cancer?

  • Hereditary prostate cancer
  • Prostate cancer, familial
  • Prostate cancer, hereditary
Clinical Trial
  • Status: Recruiting
  • Phase: N/A
  • Intervention Type: Behavioral
  • Participants: 260
  • Start Date: October 5, 2017
Culturally Adapted Cognitive Behavioral Stress and Self-Management (C-CBSM) Intervention for Prostate Cancer
Clinical Trial
  • Status: Active, not recruiting
  • Intervention Type: Other
  • Participants: 595
  • Start Date: October 23, 2014
Genetic Evaluation of Men (GEM)