Learn About Febrile Neutropenia

What is the definition of Febrile Neutropenia?
Febrile neutropenia, also called neutropenic fever, is a condition in which an individual has a fever greater than or equal to 101° F for at least an hour and a low neutrophil count. This is usually due to an infection. Febrile neutropenia commonly occurs as a complication in patients with cancer who are undergoing chemotherapy.
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What are the symptoms of Febrile Neutropenia?
Symptoms of febrile neutropenia include a fever greater than or equal to 101° F for at least an hour, a low neutrophil count, and signs and symptoms of an infection such as tenderness or pain.
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What are the current treatments for Febrile Neutropenia?
Treatment for patients with febrile neutropenia depends on their overall condition. Treatments for febrile neutropenia include medications such as fluoroquinolone plus amoxicillin/clavulanate, clindamycin, cefepime, carbapenems, piperacillin, tazobactam, vancomycin, linezolid, daptomycin, polymyxin, colistin, tigecycline, triazole, trimethoprim-sulfamethoxazole, or a nucleoside reverse transcription inhibitor.
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What are the latest Febrile Neutropenia Clinical Trials?
Fast-track Absolute Neutrophil Count in Suspected Neutropenic Fever (The FRANCiS-NF Trial): A Single-centre, Pragmatic, Open-label, Randomised, Controlled Trial

Summary: This is a comparative study for adult participants with cancer who are suspected to have neutropenic fever (or fever with low neutrophil count) in emergency department. Neutrophil is a kind of defensive white blood cell combating against infection, especially by bacteria and fungi. Low neutrophil can be part of the disease progress or secondary to some cancer treatment. These participants are at h...

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Multiple Part Clinical Trial of Brentuximab Vedotin in Classical Hodgkin Lymphoma Subjects

Summary: This trial will study two treatment combinations for classical Hodgkin lymphoma (cHL). This trial will find out if these two treatment combinations work to treat cHL. It will also find out what side effects occur. A side effect is anything the drug does besides treating cancer. This study will have three parts (Parts A, B, and C). The drugs used in Part A are a combination of targeted anticancer d...

What are the Latest Advances for Febrile Neutropenia?
Safety and efficacy of paclitaxel plus carboplatin versus paclitaxel plus cisplatin in neoadjuvant chemoradiotherapy for patients with locally advanced esophageal carcinoma: a retrospective study.
Comparison of two chemotherapy regimens in patients with newly diagnosed Ewing sarcoma (EE2012): an open-label, randomised, phase 3 trial.
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Zanubrutinib plus salvage chemotherapy for relapsed or refractory diffuse large B-cell lymphoma.