Learn About Fetal Alcohol Syndrome (FAS)

Introduction to Fetal Alcohol Syndrome (FAS) 

Fetal Alcohol Syndrome (FAS) is a preventable yet lifelong condition that arises from alcohol exposure during pregnancy. As the most severe disorder on the fetal alcohol spectrum, FAS affects a child’s physical development, cognitive abilities, and behavioral health. Its impact can be profound, influencing not only the child’s quality of life but also the emotional and social dynamics of their family. 

Although FAS is entirely avoidable, it remains a public health concern worldwide. Raising awareness about its causes, symptoms, and treatments is key to prevention and early intervention. 

What is Fetal Alcohol Syndrome?

Fetal Alcohol Syndrome occurs when alcohol consumed during pregnancy interferes with fetal development. Alcohol easily crosses the placenta, directly affecting the fetus, which lacks the enzymes needed to break it down. As a result, alcohol remains in the fetus’s bloodstream longer, impairing the growth and formation of organs—especially the brain. 

FAS typically involves three hallmark issues: distinctive facial features, stunted growth, and central nervous system (CNS) dysfunction. These outcomes are irreversible and can lead to long-term learning, behavioral, and emotional challenges. 

What Causes Fetal Alcohol Syndrome?

FAS is caused solely by alcohol exposure during pregnancy. Once alcohol enters the maternal bloodstream, it passes to the fetus, where it can harm cellular development and alter the structure and function of the brain and other organs. Because the fetus cannot metabolize alcohol efficiently, the effects are more potent and prolonged. 

Several risk factors influence the severity of FAS, including: 

  • When alcohol is consumed during pregnancy (early exposure affects facial development; later exposure may harm the brain) 
  • The quantity and frequency of alcohol use 
  • Genetic differences in alcohol metabolism 
  • Maternal health, stress, and nutritional status 

No type or amount of alcohol has been proven safe during pregnancy. While binge drinking carries a higher risk, even moderate or occasional alcohol use can be harmful—especially during the early weeks when many pregnancies go unrecognized. 

How Do You Get Fetal Alcohol Syndrome?

FAS is acquired exclusively through prenatal alcohol exposure. It is not a genetic or inherited condition, nor can it be contracted in the traditional sense. Rather, it results directly from the mother’s alcohol use during pregnancy. 

FAS can affect children of all backgrounds, but it tends to be more prevalent in populations with limited access to healthcare, education, or support services for substance use. All forms of alcohol—beer, wine, and spirits—pose a risk to the fetus. 

Signs and Symptoms of Fetal Alcohol Syndrome

Children with FAS display a range of symptoms, which often fall into three categories: facial abnormalities, growth deficits, and central nervous system problems. The severity and combination of symptoms can vary. 

Facial Features 

  • Small head circumference (microcephaly) 
  • Smooth philtrum (flattened groove between nose and upper lip) 
  • Thin upper lip 
  • Small, wide-set eyes 
  • Short, upturned nose 
  • Epicanthal folds (skin folds near the inner corners of the eyes) 

These facial characteristics tend to be most prominent between ages 2 and 10 but may become less distinct in adulthood. 

Growth Deficiencies 

  • Low birth weight 
  • Slow postnatal growth 
  • Short stature for age 
  • Inability to gain weight despite adequate nutrition 

Central Nervous System Impairments 

  • Learning disabilities 
  • Delayed speech and language development 
  • Memory and attention problems 
  • Impulse control and behavioral challenges 
  • Hyperactivity or symptoms of ADHD 
  • Poor coordination and fine motor skills 

Other complications can include vision or hearing problems, congenital heart defects, kidney abnormalities, sleep disturbances, and difficulties with emotional regulation and social behavior. 

How Is Fetal Alcohol Syndrome Diagnosed?

There is no single test that confirms FAS. Diagnosis relies on a combination of clinical evaluations, developmental assessments, and the mother’s prenatal history when available. 

Clinical and Physical Evaluation 

Doctors assess for key features of FAS, including facial abnormalities, growth delays, and signs of neurological impairment. Diagnosis does not require confirmed maternal alcohol use, though that information helps support the case. 

Developmental and Psychological Testing 

Comprehensive assessments may include: 

  • Cognitive testing (IQ) 
  • Memory, attention, and executive functioning evaluations 
  • Language and communication skill assessments 
  • Behavioral and emotional health screenings 

Imaging and Laboratory Tests 

  • Brain imaging (MRI or CT scans) may reveal structural abnormalities 
  • Genetic testing helps rule out other syndromes with overlapping symptoms (e.g., Down syndrome, Williams syndrome) 
  • Bloodwork may detect coexisting health issues 

Typically, a multidisciplinary team—pediatricians, neurologists, psychologists, and therapists—works together to confirm the diagnosis and guide intervention. 

Treatment for Fetal Alcohol Syndrome

While FAS cannot be cured, early intervention and ongoing support can improve outcomes significantly. Treatment should be personalized and often includes a combination of therapies, educational support, and medical management. 

Developmental and Educational Support 

  • Early intervention services during infancy and toddlerhood 
  • Special education programs and individualized education plans (IEPs) 
  • Speech, occupational, and physical therapy for delays 

Behavioral and Psychological Therapies 

  • Cognitive behavioral therapy (CBT) to manage emotions and behaviors 
  • Applied behavior analysis (ABA) to build adaptive skills 
  • Parent-child interaction therapy (PCIT) to strengthen relationships 
  • Social skills training to support peer interactions 

Medications 

No medications directly treat FAS, but symptoms like hyperactivity, mood swings, or sleep problems can be managed with: 

  • Stimulants for ADHD 
  • Antidepressants or anti-anxiety medications 
  • Antipsychotic medications for severe behavioral challenges 
  • Sleep aids when needed 

Family Support and Resources 

  • Parenting education and counseling 
  • Support groups and respite care 
  • Financial assistance programs 
  • Case management and advocacy services 

Transition to Adulthood 

As children with FAS reach adolescence and adulthood, support may include: 

  • Job and life skills training 
  • Supported or transitional living programs 
  • Legal guardianship when appropriate 
  • Ongoing mental health care 
Long-Term Outlook and Public Health Implications for Fetal Alcohol Syndrome

The long-term effects of FAS vary widely. Some individuals may lead semi-independent lives with appropriate support, while others may face ongoing struggles with learning, employment, relationships, and legal or substance use issues. Early, sustained intervention makes a significant difference. 

Because FAS is entirely preventable, public health initiatives focus on education, screening, and access to alcohol treatment for individuals of reproductive age. Healthcare providers should routinely discuss alcohol use with patients and offer resources to help prevent prenatal exposure. 

Additionally, promoting trauma-informed care within medical, educational, and social service systems can lead to better support and outcomes for those living with FAS. 

Conclusion

Fetal Alcohol Syndrome is a serious yet fully preventable condition caused by alcohol consumption during pregnancy. Its lifelong impact affects not only physical and cognitive development but also social and emotional well-being. While there is no cure, early diagnosis, targeted treatment, and long-term support can help improve outcomes. 

The most effective strategy remains prevention. By raising awareness, promoting alcohol-free pregnancies, and expanding access to prenatal and substance use care, communities can reduce the incidence of FAS and ensure healthier futures for children and families. 

References
  1. Jones, K. L., & Smith, D. W. (1973). Recognition of the fetal alcohol syndrome in early infancy. The Lancet, 302(7836), 999–1001. 
  2. Centers for Disease Control and Prevention (CDC). (2023). Fetal Alcohol Spectrum Disorders (FASDs). Retrieved from https://www.cdc.gov/ncbddd/fasd 
  3. American Academy of Pediatrics. (2016). Clinical report—Fetal Alcohol Spectrum Disorders. Pediatrics, 138(5), e20154264. 
  4. Streissguth, A. P., et al. (2004). Risk factors for adverse life outcomes in fetal alcohol syndrome and fetal alcohol effects. Developmental and Behavioral Pediatrics, 25(4), 228–238. 
  5. National Organization on Fetal Alcohol Syndrome (NOFAS). https://www.nofas.org 
Who are the top Fetal Alcohol Syndrome (FAS) Local Doctors?
Daniel J. Bonthius
Distinguished in Fetal Alcohol Syndrome (FAS)
Pediatrics | Pediatric Neurology
Distinguished in Fetal Alcohol Syndrome (FAS)
Pediatrics | Pediatric Neurology

Atrium Health Levine Children's Neurology

1001 Blythe Blvd., Suite 4151, 
Charlotte, NC 
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Daniel Bonthius is a Pediatrics specialist and a Pediatric Neurologist in Charlotte, North Carolina. Dr. Bonthius is rated as a Distinguished provider by MediFind in the treatment of Fetal Alcohol Syndrome (FAS). His top areas of expertise are Fetal Alcohol Syndrome (FAS), Cerebellar Hypoplasia, Subacute Sclerosing Panencephalitis, and Myoclonic Epilepsy. Dr. Bonthius is currently accepting new patients.

Elite in Fetal Alcohol Syndrome (FAS)
Elite in Fetal Alcohol Syndrome (FAS)
University Of Cape Town, 
Cape Town, WC, ZA 

Ernesta Meintjes practices in Cape Town, South Africa. Ms. Meintjes is rated as an Elite expert by MediFind in the treatment of Fetal Alcohol Syndrome (FAS). Her top areas of expertise are Fetal Alcohol Syndrome (FAS), HIV/AIDS, Spinocerebellar Degeneration and Corneal Dystrophy, and Iron Deficiency Anemia.

 
 
 
 
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Elite in Fetal Alcohol Syndrome (FAS)
Elite in Fetal Alcohol Syndrome (FAS)
University Of Cape Town, 
Cape Town, WC, ZA 

Christopher Molteno practices in Cape Town, South Africa. Mr. Molteno is rated as an Elite expert by MediFind in the treatment of Fetal Alcohol Syndrome (FAS). His top areas of expertise are Fetal Alcohol Syndrome (FAS), Spinocerebellar Degeneration and Corneal Dystrophy, Iron Deficiency Anemia, and Intrauterine Growth Restriction.

What are the latest Fetal Alcohol Syndrome (FAS) Clinical Trials?
tDCS and Cognitive Training as a Neurodevelopmental Intervention in FASD

Summary: This is a randomized placebo-controlled trial of cognitive training with transcranial direct current stimulation (tDCS) for children and adolescents (ages 8 - 17 years) with prenatal alcohol exposure (PAE).

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Supplemental Choline to Prevent and Treat Learning and Memory Deficits of Early Iron Deficiency: the SupCHO Study

Summary: BACKGROUND: Iron deficiency limits the neurodevelopmental potential of more than 200 million children each year. Iron therapy is typically started when iron deficiency anemia is first diagnosed after screening for anemia or detection of clinical symptoms of iron deficiency anemia at 12 months of age. But iron started at this time does not fully correct earlier iron-deficiency-mediated brain dysfun...