Fetal and Neonatal Alloimmune Thrombocytopenia Symptoms, Doctors, Treatments, Advances & More

Learn About Fetal and Neonatal Alloimmune Thrombocytopenia

What is the definition of Fetal and Neonatal Alloimmune Thrombocytopenia?

Fetal and neonatal alloimmune thrombocytopenia (NAIT) is a blood disorder that affects pregnant women and their babies. NAIT was first reported in the literature in 1953 and is estimated to occur in as many as 1 in 1200 live births. NAIT results in the destruction of platelets in the fetus or infant due to a mismatch between the mother's platelets and those of the baby. Certain molecules (antigens) on the surface of the baby's platelets are recognized as foreign by the mother's immune system. The mother's immune system then creates antibodies that attack and destroy the baby's platelets. Though NAIT can occur whenever the mother's blood mixes with that of the baby, it is usually triggered when the mother is exposed to the baby's blood during delivery. Many cases of NAIT are mild. Signs and symptoms may include a low platelet count (thrombocytopenia) and signs of bleeding into the skin such as petechiae and purpura. In the most severe cases, NAIT can cause bleeding episodes that may result in death or long-term disability. Bleeding episodes can occur either during pregnancy or after birth.

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What are the alternative names for Fetal and Neonatal Alloimmune Thrombocytopenia?

Fetal and neonatal alloimmune thrombocytopenia
NAIT

Who are the top Fetal and Neonatal Alloimmune Thrombocytopenia Local Doctors?

Heyu Q. Ni

Elite

Highly rated in

conditions

St. Michael's Hospital

Toronto, ON, CA

Heyu Ni practices in Toronto, Canada. Ni is rated as an Elite expert by MediFind in the treatment of Fetal and Neonatal Alloimmune Thrombocytopenia. They are also highly rated in 7 other conditions, according to our data. Their top areas of expertise are Fetal and Neonatal Alloimmune Thrombocytopenia, Thrombocytopenia, Immune Thrombocytopenia, and Purpura.

Bjorn R. Skogen

Elite

Highly rated in

conditions

University Hospital Of North Norway

Department Of Laboratory Medicine,

Tromso, NO

Bjorn Skogen practices in Tromso, Norway. Skogen is rated as an Elite expert by MediFind in the treatment of Fetal and Neonatal Alloimmune Thrombocytopenia. He is also highly rated in 2 other conditions, according to our data. His top areas of expertise are Fetal and Neonatal Alloimmune Thrombocytopenia, Thrombocytopenia, and Hemolytic Disease of the Newborn.

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Jens Kragh-Kjeldsen

Elite

Highly rated in

conditions

University Hospital Of North Norway

Department Of Clinical Immunology And Transfusion Medicine,

Lund, M, SE

Jens Kragh-Kjeldsen practices in Lund, Sweden. Kragh-Kjeldsen is rated as an Elite expert by MediFind in the treatment of Fetal and Neonatal Alloimmune Thrombocytopenia. He is also highly rated in 2 other conditions, according to our data. His top areas of expertise are Fetal and Neonatal Alloimmune Thrombocytopenia, Thrombocytopenia, Hemolytic Disease of the Newborn, and Severe Acute Respiratory Syndrome (SARS).

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What are the latest Fetal and Neonatal Alloimmune Thrombocytopenia Clinical Trials?

A Prospective, Natural History Study to Assess the Occurrence of HPA-1a Alloimmunization in Women Identified at Higher Risk for Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

Enrollment Status: Recruiting

Publish Date: August 19, 2022

Intervention Type: Other

Summary: A prospective, non-interventional, natural history study to assess the occurrence of higher FNAIT risk across a broad population of different racial and ethnic characteristics and the occurrence of HPA-1a alloimmunization in these women.

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Fetal and Neonatal Alloimmune Thrombocytopenia?