Whole-Body Photobiomodulation Therapy for Chronic Pain: a Feasibility Trial

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Chronic pain is a common long-term condition that can affect any area throughout the body. Individuals suffering with chronic pain often have associated fatigue, sleep and mood disturbances. Current treatments for chronic pain include a variety of both medicine-based approaches and non-medical approaches such as exercise and psychology treatments. Patients often take a combination of medications such as antidepressants and strong medications like morphine - which are not always effective, and often associated with several troublesome side effects. Despite physical activity being a common and helpful treatment, evidence shows that patients with chronic pain can find it difficult to engage for a variety of reasons. It would be helpful to see if other non-medication based approaches will be an acceptable treatment to those suffering with chronic pain. Photobiomodulation (PBM) therapy describes a safe, non-invasive low-energy light therapy that has been successful in treating a variety of chronic pain conditions. Cells absorb light to produce a series of reactions that culminate in pain relief, reduced inflammation, and tissue repair. Most studies examining effects of PBM have consisted of a small hand-held probe focused on specific painful areas. There are a cohort of chronic pain conditions that encompass widespread throughout the back, neck and joints, such as fibromyalgia (FM). Whole-body PBM therapy is able to treat a large area of the body in a short space of time. The main purpose of the study is to determine feasibility, with a view to guiding a definitive Randomised Controlled Trial (RCT), in terms of: feasibility of eligibility criteria, recruitment rates, acceptability of trial device in the chronic pain population, and acceptability of outcome measures.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 100
Healthy Volunteers: f
View:

∙ Patients eligible for the trial must comply with all of the following:

• Currently diagnosed or receiving treatment for a widespread chronic pain condition, including but not limited to:

‣ Axial pain of any origin

⁃ Polyathralgia of any origin

⁃ Myofascial pain of any origin

⁃ A diagnosis of chronic widespread pain or FM

• Able to provide informed written consent

• ≥18 years

• Able to commit time to the trial treatment schedule of 6 weeks

• Score as low or moderate risk on the COVID-19 risk stratification tool - applicable for the duration of the pandemic

Locations
Other Locations
United Kingdom
Sandwell and West Birmingham NHS Trust
RECRUITING
Birmingham
Time Frame
Start Date: 2022-01-12
Estimated Completion Date: 2023-09
Participants
Target number of participants: 20
Treatments
Experimental: Intervention Group
All participants in this feasibility trial will receive a course of whole-body photobiomodulation therapy (18 sessions over 6 weeks)
Related Therapeutic Areas
Sponsors
Leads: Sandwell & West Birmingham Hospitals NHS Trust

This content was sourced from clinicaltrials.gov