What is the definition of Follicular Ichthyosis?

Follicular ichthyosis is a very rare genetic skin disease characterized by excessive dry, rough, scaly skin and plugged hair follicles.

What are the symptoms for Follicular Ichthyosis?

Symptoms of follicular ichthyosis include red, dry, rough, and scaly skin, dilated hair follicles with keratin plugs that extend above the surface of the skin, and decreased or absent sebaceous glands. Follicular ichthyosis may occur in several areas of the body. Individuals with follicular ichthyosis may also have a short stature, intellectual disability, or seizures. Other symptoms of follicular ichthyosis may include overheating due to reduced sweating, limited movement due to painful skin, and secondary skin and systemic infections.

What are the current treatments for Follicular Ichthyosis?

There is no cure for follicular ichthyosis. Treatment for follicular ichthyosis is focused on moisturizing and exfoliating the skin to prevent dryness, cracking, scaling, and skin build-up. Moisturizing creams and ointments, such as lanolin creams and products containing urea, lactic acid, and other alpha hydroxy acids may be prescribed. Topical keratolytic preparations may also be prescribed to prevent flaky skin build up, along with retinoids, such as acitretin or isotretinoin, and oral antibiotics to treat secondary skin or systemic infections.

There are no recent clinical trials available for this condition. Please check back because new trials are being conducted frequently.