Non-invasive Neurostimulation as a Tool for Diagnostics and Management for Neurodegenerative Diseases
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Double blinded, sham-controlled, randomized trial on repeated transcranial alternating current brain stimulation (tACS) in neurodegenerative diseases. The investigators will evaluate whether a 4-times daily repeated stimulation with gamma tACS on the posterior parietal cortex can improve symptoms in patients with neurodegenerative diseases, including dementia with Lewy Bodies, Alzheimer's disease, idiopathic normal pressure hydrocephalus and Frontotemporal dementia.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Mild Cognitive Impairment due to Alzheimer's disease
• Dementia with Lewy Bodies
• Frontotemporal dementia
• Idiopathic normal pressure hydrocephalus (iNPH)
Locations
Other Locations
Finland
Kuopio University Hospital
RECRUITING
Kuopio
Contact Information
Primary
Eino Solje, MD, PhD
eino.solje@uef.fi
+358 17 713 311
Time Frame
Start Date: 2022-11-21
Estimated Completion Date: 2032-07
Participants
Target number of participants: 200
Treatments
Experimental: Real tACS
Four sessions (once a day, during four consecutive days) of gamma tACS (40 Hz) at 3 mA over the superior parietal cortex (Precuneus)
Placebo_comparator: Sham tACS
Four sessions of sham tACS (once a day, during four consecutive days) over the superior parietal cortex (Precuneus)
Related Therapeutic Areas
Sponsors
Leads: Kuopio University Hospital