Intervention to Promote Communication Quality of Life for Persons With Language-Led Dementia and Their Partners: A Randomized Pilot Trial

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to determine whether individually tailored speech-language telerehabilitation helps improve communication in people with primary progressive aphasia (PPA), a form of dementia that affects speech and language. The study will be offered to individuals who speak English and/or Spanish. The study will also document how acceptable and beneficial the program is to both patients and their care partners. The main questions the study aims to answer are: 1. Is the telerehabilitation program feasible and acceptable for people with PPA and their care partners? 2. Do participants with PPA and care partners find treatment beneficial? 3. Which outcome measures are most useful for evaluating changes in communication and quality of life? 4. What patterns of treatment response are seen in participants after completing the program? The program includes both speech-language therapy and training for care partners. Participants with PPA will: 1. Complete virtual communication tasks and questionnaires before and after the program 2. Take part in online speech-language therapy sessions 3. Include their care partners in some parts of the program for training and support

Eligibility
Participation Requirements
Sex: All
Minimum Age: 40
Healthy Volunteers: f
View:

• A PPA (Gorno-Tempini et al., 2011) or PPA-plus (Mesulam et al., 2001) diagnosis

• MMSE score of \> 15 and must be able to produce single monosyllabic words intelligibly.

• Must speak English, Spanish or both languages (i.e., bilingual speakers of English or Spanish)

• Hearing and vision adequate for participation in teleconference meetings

• Must have a care partner available (someone who will commit to attending teleconference sessions weekly during treatment phases)

• Partners must express willingness to attend and participate in treatment sessions including those targeting dyadic communication goals

• Partners must speak English, Spanish or both languages (i.e., bilingual speakers of English or Spanish)

• Partner's hearing and vision should be adequate for participation in teleconference meetings

Locations
United States
Texas
University of Texas
RECRUITING
Austin
Contact Information
Primary
Henry Lab Research Coordinator
aphasialab@austin.utexas.edu
512-471-3420
Backup
Grasso Lab Research Coordinator
multilingual.aphasia@austin.utexas.edu
512-232-1440
Time Frame
Start Date: 2026-01-03
Estimated Completion Date: 2027-08
Participants
Target number of participants: 25
Treatments
Other: Waitlist Control
Individuals in the waitlist-control group will undergo initial assessment followed by a waiting interval of 10 (Multi-VISTA) or 12 (Multi-LRT) weeks. Following the waiting period, they will again complete baseline assessments prior to the treatment phase (co-development of training materials and Multi-VISTA or Multi-LRT treatment).
Experimental: Immediate Treatment
Individuals in the immediate treatment group will undergo initial assessment followed immediately by the treatment phase (co-development of training materials and Multi-VISTA or Multi-LRT treatment).
Sponsors
Collaborators: National Institute on Aging (NIA), National Institutes of Health (NIH)
Leads: University of Texas at Austin

This content was sourced from clinicaltrials.gov