Stellate Ganglion Blockade for the Prevention of Atrial Fibrillation After Cardiac Surgery: A Randomized Placebo-Controlled Trial
Status: Recruiting
Location: See location...
Intervention Type: Drug, Procedure
Study Type: Interventional
Study Phase: Phase 2/Phase 3
SUMMARY
The purpose of this study is to test if a nerve block procedure called a stellate ganglion block can help decrease the chance of atrial fibrillation after surgery. Atrial fibrillation is the abnormal, fast beating of the upper chambers of the heart. Stellate ganglion blockade has shown to decrease other types of abnormal heart rhythms as well as decrease the chance of atrial fibrillation.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Healthy Volunteers: f
View:
• Patient presenting for cardiac surgery at the Mayo Clinic in Rochester, Minnesota.
• Patients scheduled to undergo mitral or aortic valve surgery with or without coronary artery bypass grafting.
Locations
United States
Minnesota
Mayo Clinic in Rochester
RECRUITING
Rochester
Time Frame
Start Date: 2023-04-19
Estimated Completion Date: 2026-12
Participants
Target number of participants: 220
Treatments
Experimental: Stellate ganglion block with local anesthetic
Subjects will receive a single injection of bupivacaine in a stellate ganglion block
Sham_comparator: Stellate ganglion block with saline placebo
Subjects will receive a single injection of saline in a stellate ganglion block
Related Therapeutic Areas
Sponsors
Leads: Mayo Clinic