Gangrene is the death of tissue in part of the body.
Gangrene happens when a body part loses its blood supply. This may happen from injury, an infection, or other causes. You have a higher risk for gangrene if you have:
The symptoms depend on the location and cause of the gangrene. If the skin is involved, or the gangrene is close to the skin, the symptoms may include:
If the affected area is inside the body (such as gangrene of the gallbladder or gas gangrene), the symptoms may include:
Gangrene requires urgent evaluation and treatment. In general, dead tissue should be removed to allow healing of the surrounding living tissue and prevent further infection. Depending on the area that has the gangrene, the person's overall condition, and the cause of the gangrene, treatment may include:
Marco Cerinic-Matucci practices in Firenze, Italy. Cerinic-Matucci is rated as an Elite expert by MediFind in the treatment of Gangrene. He is also highly rated in 51 other conditions, according to our data. His top areas of expertise are Scleroderma, Systemic Sclerosis (SSc), Gangrene, Bone Marrow Transplant, and Lung Transplant.
Domenico Ricucci practices in Cetraro, Italy. Ricucci is rated as an Elite expert by MediFind in the treatment of Gangrene. He is also highly rated in 4 other conditions, according to our data. His top areas of expertise are Gangrene, Periodontitis, Necrosis, Actinomycosis, and Tissue Biopsy.
Theodore Warkentin practices in Hamilton, Canada. Warkentin is rated as an Elite expert by MediFind in the treatment of Gangrene. He is also highly rated in 17 other conditions, according to our data. His top areas of expertise are Thrombocytopenia, Gangrene, Disseminated Intravascular Coagulation, Knee Replacement, and Coronary Artery Bypass Graft (CABG).
What to expect depends on:
The person may die if:
Complications depend on:
Complications can include:
Call your provider right away if:
Gangrene may be prevented if it is treated before the tissue damage can't be reversed. Wounds should be treated properly and watched carefully for signs of infection (such as spreading redness, swelling, or drainage) or failure to heal.
People with diabetes or blood vessel disease should routinely examine their feet for any signs of injury, infection, or change in skin color and seek care as needed.
Summary: Although it is rarely observed, necrotizing fasciitis progresses with high mortality and serious complications. Fournier's gangrene is a specific form of necrotizing fasciitis. In laboratory tests, leukocytosis or leukopenia, anemia, lymphopenia can be observed. Perianal abscess is a surgical emergency that is observed much more frequently than necrotizing fasciitis. Although Fournier's gangrene h...
Summary: The aim of this prospective randomized clinical trial is to evaluate the effect of different apical size and taper preparation (35. 04; 35. 06; 45. 04 and 45. 06) on postoperative pain at 6, 12, 24, 48 and 72 hours, and intra-canal bacterial count in patients having mandibular premolars with necrotic pulps.
Published Date: September 01, 2021
Published By: Jatin M. Vyas, MD, PhD, Associate Professor in Medicine, Harvard Medical School; Associate in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Brownlee M, Aiello LP, Sun JK, et al. Complications of diabetes mellitus. In: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. Williams Textbook of Endocrinology. 14th ed. Philadelphia, PA: Elsevier; 2020:chap 37.
Bury J. Responses to cellular injury. In: Cross SS, ed. Underwood's Pathology: A Clinical Approach. 7th ed. Philadelphia, PA: Elsevier; 2019:chap 5.
Scully R, Shah SK. Gangrene of the foot. In: Cameron AM, Cameron JL, eds. Current Surgical Therapy. 13th ed. Philadelphia, PA: Elsevier; 2020:1047-1054.