Learn About Gastritis

What is the definition of Gastritis?

Gastritis occurs when the lining of the stomach becomes inflamed or swollen.

Gastritis may last for only a short time (acute gastritis) or it may linger for months to years (chronic gastritis).

What are the causes of Gastritis?

The most common causes of gastritis are:

  • Certain medicines, such as aspirin, ibuprofen, or naproxen and other similar medicines
  • Heavy alcohol drinking
  • Infection of the stomach with a bacteria called Helicobacter pylori

Less common causes are:

  • Autoimmune disorders (such as pernicious anemia)
  • Backflow of bile into the stomach (bile reflux)
  • Cocaine use
  • Eating or drinking caustic or corrosive substances (such as poisons)
  • Viral infection, such as cytomegalovirus and herpes simplex virus (more often occurs in people with a weak immune system)

Trauma or a severe, sudden illness such as major surgery, kidney failure, or being placed on a breathing machine may cause gastritis.

What are the symptoms of Gastritis?

Many people with gastritis do not have any symptoms.

Symptoms you may notice are:

  • Loss of appetite
  • Nausea and vomiting
  • Pain in the upper part of the belly or abdomen

If gastritis is causing bleeding from the lining of the stomach, symptoms may include:

  • Black stools
  • Vomiting blood or coffee-ground-like material
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What are the current treatments for Gastritis?

Treatment depends on what is causing the problem. Some of the causes will go away over time.

You may need to stop taking aspirin, ibuprofen, naproxen, or other medicines that may be causing gastritis. Always talk to your health care provider before stopping any medicine.

You may use other over-the-counter and prescription drugs that decrease the amount of acid in the stomach, such as:

  • Antacids
  • H2 antagonists: famotidine (Pepcid), cimetidine (Tagamet), and nizatidine (Axid)
  • Proton pump inhibitors (PPIs): omeprazole (Prilosec), esomeprazole (Nexium), Iansoprazole (Prevacid), rabeprazole (AcipHex), and pantoprazole (Protonix)
  • Newer acid blockers called potassium-competitive acid blockers (PCABs) (such as vonoprazan)

Antibiotics may be used to treat gastritis caused by infection with Helicobacter pylori bacteria. They are taken with an acid blocker such as a PPI or PCAB.

Who are the top Gastritis Local Doctors?
Kazuhiko Koike
Elite in Gastritis
Elite in Gastritis
Tokyo, JP 

Kazuhiko Koike practices in Tokyo, Japan. Koike is rated as an Elite expert by MediFind in the treatment of Gastritis. Their top areas of expertise are Liver Cancer, Pancreatic Cancer, Hepatitis, Endoscopy, and Stent Placement.

Elite in Gastritis
Elite in Gastritis
Leipziger Str. 44, 
Magdeburg, ST, DE 

Peter Malfertheiner practices in Magdeburg, Germany. Mr. Malfertheiner is rated as an Elite expert by MediFind in the treatment of Gastritis. His top areas of expertise are Helicobacter Pylori Infection, Gastritis, Chronic Erosive Gastritis, Endoscopy, and Pancreaticoduodenectomy.

 
 
 
 
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Elite in Gastritis
Elite in Gastritis
Padova, IT 

Massimo Rugge practices in Padova, Italy. Mr. Rugge is rated as an Elite expert by MediFind in the treatment of Gastritis. His top areas of expertise are Gastritis, Helicobacter Pylori Infection, Viral Gastroenteritis, Endoscopy, and Colonoscopy.

What is the outlook (prognosis) for Gastritis?

The outlook depends on the cause, but is often very good.

What are the possible complications of Gastritis?

Blood loss and increased risk for gastric cancer can occur.

When should I contact a medical professional for Gastritis?

Contact your provider if you develop:

  • Pain in the upper part of the belly or abdomen that does not go away
  • Black or tarry stools
  • Vomiting blood or coffee-ground-like material
How do I prevent Gastritis?

Avoid long-term use of substances that can irritate your stomach such as aspirin, anti-inflammatory drugs, or alcohol.

What are the latest Gastritis Clinical Trials?
Evaluation of the Efficacy of Carminal on the Gastric Mucosa in Patients With Helicobacter Pylori Positive Gastritis

Summary: Eighty patients will be included and randomized in two groups, one group (40 patients) will be administered 30 ml of the supplement Carminal, once a day, plus therapy for HP gastitis and the control group (40 patients) will be given standard therapy for HP gastritis with placebo. Treatment will begin after complection of upper endoscopy with histology results from biopted gastric mucosa. Treatment...

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Safety and Efficacy Study of Betaine Hydrochloride in Treating Hypergastrinemia in Patients With Autoimmune Gastritis.

Summary: Autoimmune atrophic gastritis (AAG) is an organ-specific autoimmune disease that primarily affects the gastric body and fundus while sparing the antrum. Its characteristics include destruction of gastric wall cells, loss of intrinsic factors, and atrophy of the gastric mucosa. Endoscopic examination reveals features of reverse atrophy, with significant atrophy in the gastric body and fundus, appea...

Who are the sources who wrote this article ?

Published Date: January 24, 2025
Published By: Jenifer K. Lehrer, MD, Gastroenterologist, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Feldman M, Jensen PJ, Howden CW. Gastritis and gastropathy. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 52.

Kuipers EJ. Acid peptic disease. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 125.