Atrophic Gastritis Predicts the Risk of Gastric Cancer: a Prospective Cohort Study

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY

Despite declining incidence rates, gastric cancer (GC) ranks the fourth leading cause of cancer-related mortality and the fifth most common cancer worldwide, with the highest incidence reported in Eastern Asia. The 5-year overall survival rate of early GC exceeds 90%, which was well above advanced GC. Most intestinal-type GCs follow the Correa cascade-inflammation,atrophy, intestinal metaplasia (IM), dysplasia and subsequent carcinoma. The presence of gastric mucosal atrophy and intestinal metaplasia are important risk factors for GC. The purpose of this study was to investigate the incidence of GC attributed to atrophic gastritis in a region with high incidence of GC.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 70
Healthy Volunteers: f
View:

• Ability and willingness to participate in the study and to sign and give informed consent

• Biopsies were collected based on the recommendation of updated Sydney system

Locations
Other Locations
China
Renji Hospital, School of Medicine, Shanghai Jiao Tong University
RECRUITING
Shanghai
Time Frame
Start Date: 2023-12-15
Estimated Completion Date: 2034-12-31
Participants
Target number of participants: 2042
Treatments
OLGA 0-I
OLGA II
OLGA III-IV
Sponsors
Leads: Shanghai Jiao Tong University School of Medicine

This content was sourced from clinicaltrials.gov

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