Pilot Study of Dental Erosion as a Non-invasive Biomarker of Esophagogastric Cancer

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The researchers are doing this study to find out more about what may lead to the loss of tooth enamel (the thin outer covering of the tooth) and how often it happens in people with esophagogastric cancer, colorectal cancer, pancreatic cancer, breast cancer, head and neck cancer, or non-small cell lung cancer, or a healthy volunteer.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Subject is willing and able to provide written informed consent.

• Patients with a history of esophagogastric, HNSCC, PDAC, CRC, or NSCLC or healthy controls

• Patients must be able to fully comprehend and complete the survey and be willing to have pictures taken of their teeth with a camera or intra-oral camera.

• Patients must be able to understand English language or have access to adequate translation services.

• Age ≥ 18 years old.

Locations
United States
New York
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
RECRUITING
New York
Contact Information
Primary
Steven Maron, MD
marons@mskcc.org
646-888-6780
Backup
Luis Diaz, MD
646-888-4641
Time Frame
Start Date: 2022-11-03
Estimated Completion Date: 2025-11
Participants
Target number of participants: 300
Treatments
Experimental: Patients diagnosed with esophagogastric cancer
Patients have completed the intervention once completing the survey, undergoing dental imaging and future patients will also provide an optional saliva sample.
Experimental: Patients diagnosed with colorectal, pancreatic, breast, head and neck, or non-small cell lung cancer
Patients undergo consenting and dental imaging during their routine visits at MSK.
Experimental: Healthy volunteers who have not been diagnosed with cancer
Healthy controls will be defined as those without a known or suspected invasive cancer history and excluding those undergoing a procedure for symptomatic reflux.
Sponsors
Leads: Memorial Sloan Kettering Cancer Center

This content was sourced from clinicaltrials.gov