Germ Cell Tumor Overview

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Learn About Germ Cell Tumor

View Main Condition: Brain Tumor

What is the definition of Germ Cell Tumor?
Malignant germ cell tumors are rare cancerous masses that can grow in the ovaries in girls and testes in boys as well as other parts of the body, such as the chest, abdomen, lower back, and brain. There are several types of malignant germ cell tumors, such as teratomas, germinomas, endodermal sinus tumor or yolk sac tumors, choriocarcinoma, and embryonal carcinoma.
What are the symptoms of Germ Cell Tumor?
Symptoms of malignant germ cell tumors depend on the size and location of the tumor and may include a solid testicular mass, with or without pain, in boys; a solid ovarian mass with abdominal pain in girls; a mass on the lower back or near the anus in an infant; a mass in the chest with associated respiratory distress; early puberty or vaginal bleeding at a very young age; constipation; incontinence; leg weakness; and abnormal testicular size or shape.
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What are the current treatments for Germ Cell Tumor?
Treatment for malignant germ cell tumors depends on the size and location of the tumor as well how advanced the cancer is and may include surgery, radiation therapy, chemotherapy (cisplation, etoposide, and bleomycin), hormonal replacement, and bone marrow transplantation. Treatment for relapsed malignant germ cell tumors may include additional chemotherapy with paclitaxel, ifosfamide, and carboplation followed by autologous stem cell transplantation.
Who are the top Germ Cell Tumor Local Doctors?
Elite in Germ Cell Tumor
Furqan A. Shaikh
Elite in Germ Cell Tumor
Furqan A. Shaikh
555 University Ave, 
Toronto, ON, CA 

Furqan Shaikh practices in Toronto, Canada. Mr. Shaikh is rated as an Elite expert by MediFind in the treatment of Germ Cell Tumor. His top areas of expertise are Germ Cell Tumor, Retinoblastoma, Testicular Yolk Sac Tumor, and Testicular Cancer.

Elite in Germ Cell Tumor
Dr. James F. Amatruda
Pediatric Hematology Oncology
Elite in Germ Cell Tumor
Dr. James F. Amatruda
Pediatric Hematology Oncology
1935 Medical District Dr, 
Dallas, TX 
214-456-7000
Languages Spoken:
English
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James Amatruda is a Pediatric Hematologist Oncology provider in Dallas, Texas. Dr. Amatruda is rated as an Elite provider by MediFind in the treatment of Germ Cell Tumor. His top areas of expertise are Germ Cell Tumor, Teratoma of the Mediastinum, Ewing Sarcoma, Osteosarcoma, and Orchiectomy.

 
 
 
 
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Elite in Germ Cell Tumor
Dr. Carlos A. Rodriguez
Pediatric Hematology Oncology
Elite in Germ Cell Tumor
Dr. Carlos A. Rodriguez
Pediatric Hematology Oncology
262 Danny Thomas Pl, 
Memphis, TN 
901-595-3300
Languages Spoken:
English
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Carlos Rodriguez is a Pediatric Hematologist Oncology provider in Memphis, Tennessee. Dr. Rodriguez is rated as an Elite provider by MediFind in the treatment of Germ Cell Tumor. His top areas of expertise are Germ Cell Tumor, Retinoblastoma, Langerhans Cell Histiocytosis, Hepatectomy, and Tissue Biopsy.

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What are the latest Germ Cell Tumor Clinical Trials?
A Single-center, Single-arm, Open-label Study of the Combination of Teniposide Injection and Cisplatin in the Treatment of Newly Diagnosed Patients With Central Malignant Germ Cell Tumors.
A Single-center, Single-arm, Open-label Study of the Combination of Teniposide Injection and Cisplatin in the Treatment of Newly Diagnosed Patients With Central Malignant Germ Cell Tumors.
Enrollment Status: Recruiting
Publish Date: September 23, 2025
Intervention Type: Drug
Study Phase: Phase 2

Summary: This trial is a prospective single arm intervention study, conducting clinical research on marketed drugs. Adverse drug reactions are controllable and the risk is low, with an estimated total of 40 cases. The main objective is to evaluate the safety and efficacy of teniposide combined with cisplatin in the treatment of newly diagnosed central malignant germ cell tumors, and to conduct drug monitor...

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