Learn About Giant Cell Arteritis (GCA)

What is the definition of Giant Cell Arteritis (GCA)?
Giant cell arteritis (GCA) is a form of vasculitis, a group of disorders that cause inflammation of blood vessels. GCA most commonly affects the arteries of the head (especially the temporal arteries, located on each side of the head), but arteries in other areas of the body can also become inflamed. The inflammation causes the arteries to narrow, resulting in poor blood flow. Symptoms when arteries in the head are involved may include a throbbing headache on one side or the back of the head, tenderness of the scalp, flu-like symptoms, and/or problems with eyesight. Symptoms when other arteries are involved depend on the location of those arteries. The cause of GCA is still being studied, but it is thought to involve the immune system mistakenly attacking the artery walls. Several genetic and environmental factors may increase a person's risk to develop GCA. GCA may develop with or after another inflammatory disorder known as polymyalgia rheumatica.
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What are the alternative names for Giant Cell Arteritis (GCA)?
  • Giant cell arteritis
  • Arteritis cranialis
  • Arteritis temporalis
  • Cranial arteritis
  • GCA
  • Horton's arteritis
  • Horton's giant cell arteritis
  • Horton's temporal arteritis
  • Horton’s disease
  • Horton’s syndrome
  • Temporal arteritis
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What are the latest Giant Cell Arteritis (GCA) Clinical Trials?
Study of T Lymphocytes in the Mucosa in Giant-cell Arteritis (GCA) - Giant Cell Arteritis and Mucosal Associated Invariant T Cells
Summary: Giant-cell arteritis (GCA) is the most frequent vasculitis after 50 years. Corticosteroid therapy is the reference treatment for GCA. This treatment is highly effective but must be maintained for 12 to 24 months to avoid relapses, which causes the onset of numerous adverse effects in this elderly population.~Currently clinicians have no way to estimate this risk of relapse during the treatment of ...
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A Head-to-head Comparison of Ultrasound Versus Temporal Artery Biopsy in the Diagnosis of Giant Cell Arteritis
Summary: Giant cell arteritis - Optimization of diagnostics
Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Giant Cell Arteritis (GCA)?
Intravenous tocilizumab for the treatment of giant cell arteritis: a phase Ib dose-ranging pharmacokinetic bridging study.
Summary: Intravenous tocilizumab for the treatment of giant cell arteritis: a phase Ib dose-ranging pharmacokinetic bridging study.
Tocilizumab for giant cell arteritis.
Summary: Tocilizumab for giant cell arteritis.
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Does Tocilizumab Influence Ophthalmic Outcomes in Giant Cell Arteritis?
Summary: Does Tocilizumab Influence Ophthalmic Outcomes in Giant Cell Arteritis?