Learn About Giant Congenital Nevus

What is the definition of Giant Congenital Nevus?

A congenital pigmented or melanocytic nevus is a dark-colored, often hairy, patch of skin. It is present at birth or appears in the first year of life.

A giant congenital nevus is smaller in infants and children, but it usually continues to grow as the child grows. A giant pigmented nevus is larger than 15 inches (40 centimeters) once it stops growing.

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What are the alternative names for Giant Congenital Nevus?

Congenital giant pigmented nevus; Giant hairy nevus; Giant pigmented nevus; Bathing trunk nevus; Congenital melanocytic nevus - large

What are the causes of Giant Congenital Nevus?

These marks are thought to be caused by a localized increase in melanocytes as a baby grows in the womb. Melanocytes are the skin cells that produce melanin, which gives skin its color. A nevus has an increased amount of melanocytes.

The condition is thought to be caused by a gene defect.

The condition may occur with:

  • Other nevi (moles)
  • Involvement of the membranes of the brain and spinal cord when the nevus affects a very large area

Smaller congenital pigmented or melanocytic nevi are common in children and do not cause problems most of the time. Larger or giant nevi are rare.

What are the symptoms of Giant Congenital Nevus?

A nevus will appear as a dark-colored patch with any of the following:

  • Brown to bluish-black color
  • Hair
  • Regular or uneven borders
  • Smaller affected areas near the larger nevus (maybe)
  • Smooth, irregular, or wart-like skin surface

Nevi are commonly found on the upper or lower parts of the back or the abdomen. They may also be found on the:

  • Arms
  • Legs
  • Mucus membranes
  • Palms or soles
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What are the current treatments for Giant Congenital Nevus?

You will need to have regular exams to check for skin cancer.

Surgery to remove the nevus can be done for cosmetic reasons or if your provider thinks it may become skin cancer. Skin grafting is also done when needed. Larger nevi may need to be removed in several stages.

Lasers and dermabrasion (rubbing them off) can also be used to improve appearance. These treatments may not remove the whole birthmark, so it may be harder to detect skin cancer (melanoma). Talk to your doctor about the pros and cons of surgery for you.

Treatment may be helpful if the birthmark causes emotional problems because of how it looks.

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What is the outlook (prognosis) for Giant Congenital Nevus?

Skin cancer may develop in some people with large or giant nevi. The cancer risk is higher for nevi that are larger in size. However, it isn't known if removing the nevus reduces that risk.

What are the possible complications of Giant Congenital Nevus?

Having a giant nevus may lead to:

  • Depression and other emotional problems if the nevi affect appearance
  • Skin cancer (melanoma)
When should I contact a medical professional for Giant Congenital Nevus?

This condition is usually diagnosed at birth. Talk to your child's provider if your child has a large pigmented area anywhere on their skin.

Congenital nevus on the abdomen
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What are the Latest Advances for Giant Congenital Nevus?

There is no recent research available for this condition. Please check back because thousands of new papers are published every week and we strive to find and display the most recent relevant research as soon as it is available.

Who are the sources who wrote this article ?

Published Date: November 04, 2020
Published By: Elika Hoss, MD, Senior Associate Consultant, Mayo Clinic, Scottsdale, AZ. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Dinulos JGH. Nevi and malignant melanoma. In: Dinulos JGH, ed. Habif's Clinical Dermatology. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 22.

Patterson JW. Lentigines, nevi, and melanomas. In: Patterson JW, ed. Weedon's Skin Pathology. 5th ed. Philadelphia, PA: Elsevier; 2021:chap 33.