Efficacy of Phacogoniotomy in Medically-controlled Primary Open-angle Glaucoma With Cataract a Multicenter Non-inferiority Randomized Controlled Trial
The goal of this multicenter non-inferiority randomized controlled trial is to compare the efficacy of phacoemulsification with intraocular lens implantation (PEI) combined with goniotomy (GT) and PEI combined with medical therapy (MED) in the treatment of medically-controlled primary open-angle glaucoma (POAG) with cataract. The main questions it aims to answer are: * Whether the PEI+GT was non-inferior to PEI+MED with regard to the intraocular pressure lowering effect in medically-controlled POAG. * Whether the PEI+GT has value of health economics. Participants will be randomized to receive either PEI+GT or PEI+MED, and followed up with a 1-year period as a primary outcome.
• 40 ≤ Age ≤ 85 years, gender unrestricted.
• Diagnosed with POAG.
• Controlled IOP under 1 to 4 topical hypotensive medications, IOP ≤ 24 mmHg
• Mean deviation (MD) for perimetry ≥ -16dB.
• Presence of clinically significant cataract and best-corrected visual acuity measured using the ETDRS chart ≤ 0.63.
• Voluntary participation of the patient in this study, signing an informed consent form, and agreeing to follow-up visits according to the study protocol.