Pigment-Dispersion Syndrome
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Pigment-Dispersion Syndrome Overview

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Learn About Pigment-Dispersion Syndrome

What is the definition of Pigment-Dispersion Syndrome?
Pigment-dispersion syndrome is an eye disorder that occurs when pigment granules that normally adhere to the back of the iris (the colored part of the eye) flake off into the clear fluid produced by the eye (aqueous humor). These pigment granules may flow towards the drainage canals of the eye, slowly clogging them and raising the pressure within the eye (intraocular pressure or IOP). This rise in eye pressure can cause damage to the optic nerve (the nerve in the back of the eye that carries visual images to the brain). If the optic nerve becomes damaged, Pigment-dispersion syndrome becomes pigmentary glaucoma. This happens in about 30% of cases. While men and women are affected in equal numbers, men develop pigmentary glaucoma up to 3 times more often than women. Myopia (nearsightedness) appears to be an important risk factor in the development of Pigment-dispersion syndrome and is present in up to 80% of affected individuals. The condition may be sporadic or follow an autosomal dominant pattern of inheritance with reduced penetrance . At least one gene locus on chromosome 7 has been identified.
What are the alternative names for Pigment-Dispersion Syndrome?
  • Pigment-dispersion syndrome
Who are the top Pigment-Dispersion Syndrome Local Doctors?
Elite in Pigment-Dispersion Syndrome
Dr. Davinder S. Grover
Ophthalmology
Elite in Pigment-Dispersion Syndrome
Dr. Davinder S. Grover
Ophthalmology

Glaucoma Associates Of Texas - Dallas

10740 N Central Expy, Ste 300, 
Dallas, TX 
214-360-0000
Languages Spoken:
English
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Davinder Grover is an Ophthalmologist practicing medicine in Dallas, Texas. Dr. Grover is rated as an Elite provider by MediFind in the treatment of Pigment-Dispersion Syndrome. He is also highly rated in 15 other conditions, according to our data. His clinical expertise encompasses Glaucoma, Pigment-Dispersion Syndrome, Ocular Hypertension (OHT), Trabeculectomy, and Iridectomy.

Elite in Pigment-Dispersion Syndrome
Dr. Jonathan S. Myers
Ophthalmology
Elite in Pigment-Dispersion Syndrome
Dr. Jonathan S. Myers
Ophthalmology

Ophthalmology - Wills Eye Hospital

840 Walnut Street, Floor 10, 
Philadelphia, PA 
215-928-3197
Languages Spoken:
English
See accepted insurances
Accepting New Patients

Jonathan Myers is an Ophthalmologist practicing medicine in Philadelphia, Pennsylvania. Dr. Myers is rated as an Elite provider by MediFind in the treatment of Pigment-Dispersion Syndrome. He is also highly rated in 9 other conditions, according to our data. His clinical expertise encompasses Glaucoma, Ocular Hypertension (OHT), Pigment-Dispersion Syndrome, Trabeculectomy, and Iridectomy. Dr. Myers is board certified in Ophthalmology. Dr. Myers is currently accepting new patients.

 
 
 
 
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Elite in Pigment-Dispersion Syndrome
Dr. Victoria M. Addis
Ophthalmology
Elite in Pigment-Dispersion Syndrome
Dr. Victoria M. Addis
Ophthalmology

Scheie Eye Institute Radnor

145 King Of Prussia Road, Floor 2, Suite 204 South, 
Radnor, PA 
215-662-8100
Languages Spoken:
English
See accepted insurances
Accepting New Patients

Victoria Addis is an Ophthalmologist practicing medicine in Radnor, Pennsylvania. Dr. Addis is rated as an Elite provider by MediFind in the treatment of Pigment-Dispersion Syndrome. She is also highly rated in 12 other conditions, according to our data. Her clinical expertise encompasses Glaucoma, Ocular Hypertension (OHT), Pigment-Dispersion Syndrome, Trabeculectomy, and Iridectomy. Dr. Addis is board certified in Ophthalmology, 2016. Dr. Addis is currently accepting new patients.

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What are the latest Pigment-Dispersion Syndrome Clinical Trials?
Novel Telehealth Technologies to Detect and Manage Glaucoma and Vision-threatening Eye Diseases in High-risk Populations
Novel Telehealth Technologies to Detect and Manage Glaucoma and Vision-threatening Eye Diseases in High-risk Populations
Enrollment Status: Recruiting
Publish Date: April 15, 2026
Intervention Type: Other
Study Phase: Not Applicable

Summary: The vast majority of glaucoma cases in the United States go undetected and untreated until the late stages of the disease. Open-angle glaucoma is a progressive condition that is asymptomatic in its early to moderate stages and may be amenable to screening through telemedicine-based approaches. This study is a randomized trial to evaluate whether glaucoma screening with established tests (e.g., opt...

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Direct Selective Laser Trabeculoplasty Providing Effective Intraocular Pressure Reduction in Pigmentary Glaucoma Patients
Direct Selective Laser Trabeculoplasty Providing Effective Intraocular Pressure Reduction in Pigmentary Glaucoma Patients
Enrollment Status: Recruiting
Publish Date: April 09, 2026
Intervention Type: Device

Summary: This study is a single-site, single-arm, prospective, observational study of IOP reduction after DSLT. Subjects will be assessed up to 12 months post-operatively. Clinical evaluations will include IOP and number of glaucoma medications.

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center