Pigment-Dispersion Syndrome
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Pigment-Dispersion Syndrome Overview

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Learn About Pigment-Dispersion Syndrome

What is the definition of Pigment-Dispersion Syndrome?
Pigment-dispersion syndrome is an eye disorder that occurs when pigment granules that normally adhere to the back of the iris (the colored part of the eye) flake off into the clear fluid produced by the eye (aqueous humor). These pigment granules may flow towards the drainage canals of the eye, slowly clogging them and raising the pressure within the eye (intraocular pressure or IOP). This rise in eye pressure can cause damage to the optic nerve (the nerve in the back of the eye that carries visual images to the brain). If the optic nerve becomes damaged, Pigment-dispersion syndrome becomes pigmentary glaucoma. This happens in about 30% of cases. While men and women are affected in equal numbers, men develop pigmentary glaucoma up to 3 times more often than women. Myopia (nearsightedness) appears to be an important risk factor in the development of Pigment-dispersion syndrome and is present in up to 80% of affected individuals. The condition may be sporadic or follow an autosomal dominant pattern of inheritance with reduced penetrance . At least one gene locus on chromosome 7 has been identified.
What are the alternative names for Pigment-Dispersion Syndrome?
  • Pigment-dispersion syndrome
Who are the top Pigment-Dispersion Syndrome Local Doctors?
Elite in Pigment-Dispersion Syndrome
Elite in Pigment-Dispersion Syndrome
Referral may be required

Glaucoma Associates Of Texas - Dallas

10740 N Central Expy, Ste 300, 
Dallas, TX 
214-360-0000
Languages Spoken:
English
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Davinder Grover is an Ophthalmologist practicing medicine in Dallas, Texas. Dr. Grover is rated as an Elite provider by MediFind in the treatment of Pigment-Dispersion Syndrome. He is also highly rated in 15 other conditions, according to our data. His clinical expertise encompasses Glaucoma, Pigment-Dispersion Syndrome, Ocular Hypertension (OHT), Trabeculectomy, and Cataract Removal.

Elite in Pigment-Dispersion Syndrome
Dr. Victoria M. Addis
Ophthalmology
Elite in Pigment-Dispersion Syndrome
Dr. Victoria M. Addis
Ophthalmology
Referral may be required

Scheie Eye Institute Radnor

145 King Of Prussia Road, Floor 2, Suite 204 South, 
Radnor, PA 
215-662-8100
Languages Spoken:
English
See accepted insurances
Accepting New Patients

Victoria Addis is an Ophthalmologist practicing medicine in Radnor, Pennsylvania. Dr. Addis is rated as an Elite provider by MediFind in the treatment of Pigment-Dispersion Syndrome. She is also highly rated in 12 other conditions, according to our data. Her clinical expertise encompasses Glaucoma, Ocular Hypertension (OHT), Pigment-Dispersion Syndrome, Trabeculectomy, and Iridectomy. Dr. Addis is board certified in Ophthalmology, 2016. Dr. Addis is currently accepting new patients.

 
 
 
 
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Elite in Pigment-Dispersion Syndrome
Dr. Nazlee Zebardast
Ophthalmology
Elite in Pigment-Dispersion Syndrome
Dr. Nazlee Zebardast
Ophthalmology
Referral may be required

Mass Eye And Ear, Longwood Eye Care

800 Huntington Avenue, 
Boston, MA 
617-573-3689
Languages Spoken:
English
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Nazlee Zebardast is an Ophthalmologist practicing medicine in Boston, Massachusetts. Dr. Zebardast is rated as an Elite provider by MediFind in the treatment of Pigment-Dispersion Syndrome. She is also highly rated in 6 other conditions, according to our data. Her clinical expertise encompasses Glaucoma, Ocular Hypertension (OHT), Pigment-Dispersion Syndrome, Trabeculectomy, and Iridectomy. Dr. Zebardast is board certified in Ophthalmology.

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What are the latest Pigment-Dispersion Syndrome Clinical Trials?
A Prospective, Multicenter Clinical Study to Evaluate the Safety and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Subjects With Glaucoma
A Prospective, Multicenter Clinical Study to Evaluate the Safety and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Subjects With Glaucoma
Enrollment Status: Recruiting
Publish Date: June 18, 2026
Intervention Type: Device
Study Phase: Phase 3

Summary: Glaucoma is the second most common cause of blindness in the world, second only to cataracts. This study will assess how safe and effective a glaucoma gel stent is when implanted using the ab interno (inside the eye) and ab externo (outside the eye) approach. Adverse events and intraocular pressure will be assessed. XEN63 is an investigational device for the treatment of intraocular pressure (IOP)...

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A Prospective, Multicenter, Randomized Clinical Trial to Evaluate the Safety and Effectiveness of ELIOS vs Competitor in Patients With Open-Angle Glaucoma Undergoing Cataract Surgery
A Prospective, Multicenter, Randomized Clinical Trial to Evaluate the Safety and Effectiveness of ELIOS vs Competitor in Patients With Open-Angle Glaucoma Undergoing Cataract Surgery
Enrollment Status: Recruiting
Publish Date: June 17, 2026
Intervention Type: Procedure
Study Phase: Not Applicable

Summary: The primary study objective is to compare the effectiveness of the combination of phacoemulsification with intraocular lens implant with ELIOS or competitor device in reducing IOP at 12 months postoperatively.

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center