Gliomatosis Cerebri

Symptoms, Doctors, Treatments, Research & More

Condition 101

What is the definition of Gliomatosis Cerebri?

Gliomatosis cerebri is a type of malignant (cancerous) brain tumor called a glioblastoma that develops from a specific type of brain cell called an astrocyte. It involves at least three sections (lobes) within the main part of the brain (cerebrum). It may also affect both sides of the cerebrum as well as the nerve cells within the brain (grey matter). There are two types of gliomatosis cerebri. Type 1 (classic form) is characterized by scattered and widespread tumor cells and no apparent mass or tumor, while type 2 has similar characteristics in addition to a detectable mass or tumor. Signs and symptoms of gliomatosis cerebri may include personality changes, memory disturbance, headaches, and seizures. Because this type of cancer can be found in many areas of the brain, it can be challenging to treat. Treatment might include surgery to remove areas of the brain affected (when possible), radiation therapy, and chemotherapy.

Latest Research

Latest Advance
  • Condition: Diffuse Astrocytoma with Malignant Progression
  • Journal: No shinkei geka. Neurological surgery
  • Treatment Used: Temozolomide Monotherapy with Radiochemotherapy
  • Number of Patients: 1
  • Published —
This case report describes a patient with diffuse astrocytoma that rapidly progressed after a long-term temozolomide monotherapy.
Latest Advance
  • Condition: Recurrent Glioblastoma
  • Journal: Journal for immunotherapy of cancer
  • Treatment Used: Axitinib plus Avelumab
  • Number of Patients: 54
  • Published —
This study tested the safety and efficacy of using axitinib plus avelumab to treat patients with recurrent glioblastoma.