Gliosarcoma Overview

Save information for later
Sign Up

Learn About Gliosarcoma

View Main Condition: Brain Tumor

What is the definition of Gliosarcoma?
Gliosarcoma is a rare type of brain tumor that develops from glial cells, which are specialized cells that surround and support neurons (nerve cells). Unlike gliomas, gliosarcomas have a higher likelihood to spread to the lymph nodes, lungs, and liver. 
What are the causes of Gliosarcoma?
The cause of gliosarcomas is still unknown. However, gliosarcomas generally tend to be more common in adults than children. Men are also more likely to develop gliosarcomas than women.
What are the symptoms of Gliosarcoma?
The symptoms of gliosarcomas primarily depend on the tumor's location as well as how much the tumor has spread. Common symptoms include headaches, memory difficulties, fatigue, numbness, balance issues, and seizures. 
Not sure about your diagnosis?
Check Your Symptoms
What are the current treatments for Gliosarcoma?
Treatment for gliosarcoma may include surgery, radiation therapy, and/or chemotherapy. Surgery to remove as much of the tumor as possible is generally the first step in treating gliosarcoma. However, if a tumor is located near a sensitive area in the brain, surgery may not be possible at all. Radiation therapy often follows surgery for the treatment of gliosarcoma. Radiation therapy involves the use of high-energy beams, including X-rays or protons, to destroy tumor cells. Chemotherapy involves the use of drugs, either taken orally or injected through a vein, to kill tumor cells. Chemotherapy is often used in combination with radiation therapy.
Who are the top Gliosarcoma Local Doctors?
Elite in Gliosarcoma
Dr. John F. De Groot
Neurology
Elite in Gliosarcoma
Dr. John F. De Groot
Neurology

Ucsf Medical Group Business Services

521 Parnassus Ave, 
San Francisco, CA 
415-476-1000
Languages Spoken:
English
See accepted insurances
Offers Telehealth

John De Groot is a Neurologist in San Francisco, California. Dr. De Groot is rated as an Elite provider by MediFind in the treatment of Gliosarcoma. His top areas of expertise are Glioblastoma, Astrocytoma, Glioma, and Brain Tumor.

Elite in Gliosarcoma
Dr. Andrew E. Sloan
Neurosurgery
Elite in Gliosarcoma
Dr. Andrew E. Sloan
Neurosurgery

Premier Health Specialists Inc

30 E Apple St, Suite 5254a, 
Dayton, OH 
937-208-4200
Languages Spoken:
English, Haitian Creole, Spanish
See accepted insurances
Accepting New Patients
Offers Telehealth

Andrew Sloan is a Neurosurgery provider in Dayton, Ohio. Dr. Sloan is rated as an Elite provider by MediFind in the treatment of Gliosarcoma. His top areas of expertise are Glioblastoma, Astrocytoma, Glioma, Awake Craniotomy, and Gamma Knife Radiosurgery. Dr. Sloan is currently accepting new patients.

 
 
 
 
Learn about our expert tiers
Learn More
Henry Brem
Elite in Gliosarcoma
Dr. Henry Brem
Neurosurgery
Elite in Gliosarcoma
Dr. Henry Brem
Neurosurgery

Johns Hopkins Outpatient Center

601 North Caroline Street, Floor 5, Floor 5, 
Baltimore, MD 
410-955-6406
Languages Spoken:
English, Hebrew
See accepted insurances
Offers Telehealth

Henry Brem is a Neurosurgery provider in Baltimore, Maryland. Dr. Brem is rated as an Elite provider by MediFind in the treatment of Gliosarcoma. His top areas of expertise are Gliosarcoma, Glioma, Brain Tumor, Endoscopic Transnasal Transsphenoidal Surgery, and Osteotomy.

View All Doctors
How do I prevent Gliosarcoma?
There is no known way to prevent gliosarcomas. However, if you develop any symptoms common to a gliosarcoma, it is recommended to make an appointment with your doctor to be properly diagnosed.
What are the latest Gliosarcoma Clinical Trials?
A First-in-human Phase I Single-agent Dose-escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
A First-in-human Phase I Single-agent Dose-escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
Who is this study for: Patients with recurrent and rare primary central nervous system neoplasms
Enrollment Status: Recruiting
Publish Date: December 17, 2025
Intervention Type: Drug
Study Drug: ONC206
Study Phase: Phase 1

Summary: The primary objective of this Phase 1, open-label, dose-escalation, and exploratory study is to evaluate the safety and tolerability profile (establish the maximum-tolerated dose) and evaluate the occurrence of dose-limiting toxicities (DLTs) following single weekly or multiple-day weekly dose regimens of single-agent, oral ONC206 in patients with recurrent, primary central nervous system (CNS) ne...

Match to trials
Find the right clinical trials for you in under a minute
Get started
Phase Ib Trial of ABBV-637 or ABBV-155 in Combination With ERAS-801 for Glioblastoma With Amplification of the Epidermal Growth Factor Receptor
Phase Ib Trial of ABBV-637 or ABBV-155 in Combination With ERAS-801 for Glioblastoma With Amplification of the Epidermal Growth Factor Receptor
Enrollment Status: Recruiting
Publish Date: December 02, 2025
Intervention Type: Drug, Radiation
Study Phase: Phase 1

Summary: The researchers are doing this study to find out whether the drugs ABBV-637 and ABBV-155 are safe treatments that cause few or mild side effects when given alone or in combination with ERAS-801 in people with recurrent GBM.

View All Clinical Trials
What are some Advocacy Organizations?
keep-punching-brain-cancer

Keep Punching supports patients, healthcare providers, and researchers in their fight to prevent and eradicate brain cancer and minimize treatment-related side effects that may adversely impact function and comfort.