Gliosarcoma
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Gliosarcoma Overview

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Learn About Gliosarcoma

View Main Condition: Brain Tumor

What is the definition of Gliosarcoma?
Gliosarcoma is a rare type of brain tumor that develops from glial cells, which are specialized cells that surround and support neurons (nerve cells). Unlike gliomas, gliosarcomas have a higher likelihood to spread to the lymph nodes, lungs, and liver. 
What are the causes of Gliosarcoma?
The cause of gliosarcomas is still unknown. However, gliosarcomas generally tend to be more common in adults than children. Men are also more likely to develop gliosarcomas than women.
What are the symptoms of Gliosarcoma?
The symptoms of gliosarcomas primarily depend on the tumor's location as well as how much the tumor has spread. Common symptoms include headaches, memory difficulties, fatigue, numbness, balance issues, and seizures. 
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What are the current treatments for Gliosarcoma?
Treatment for gliosarcoma may include surgery, radiation therapy, and/or chemotherapy. Surgery to remove as much of the tumor as possible is generally the first step in treating gliosarcoma. However, if a tumor is located near a sensitive area in the brain, surgery may not be possible at all. Radiation therapy often follows surgery for the treatment of gliosarcoma. Radiation therapy involves the use of high-energy beams, including X-rays or protons, to destroy tumor cells. Chemotherapy involves the use of drugs, either taken orally or injected through a vein, to kill tumor cells. Chemotherapy is often used in combination with radiation therapy.
Who are the top Gliosarcoma Local Doctors?
Elite in Gliosarcoma
Dr. Henry Brem
Neurosurgery
Elite in Gliosarcoma
Dr. Henry Brem
Neurosurgery
Referral may be required

Johns Hopkins Outpatient Center

601 North Caroline Street, Floor 5, Floor 5, 
Baltimore, MD 
410-955-6406
Languages Spoken:
English, Hebrew
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Henry Brem is a Neurosurgery provider practicing medicine in Baltimore, Maryland. Dr. Brem is rated as an Elite provider by MediFind in the treatment of Gliosarcoma. He is also highly rated in 16 other conditions, according to our data. His clinical expertise encompasses Gliosarcoma, Glioma, Gliomatosis Cerebri, Osteotomy, and Posterior Fossa Decompression. Dr. Brem is board certified in American Board Of Neurological Surgery.

Elite in Gliosarcoma
Elite in Gliosarcoma
Referral may be required

Dana-Farber Cancer Institute, Center For Neuro-Oncology

450 Brookline Avenue, 
Boston, MA 
617-632-2166
Languages Spoken:
English
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Offers Telehealth

Patrick Wen is a Neurologist practicing medicine in Boston, Massachusetts. Dr. Wen is rated as an Elite provider by MediFind in the treatment of Gliosarcoma. He is also highly rated in 26 other conditions, according to our data. His clinical expertise encompasses Glioblastoma, Astrocytoma, Glioma, and Brain Tumor. Dr. Wen is board certified in Neurology and Neuro-Oncology.

 
 
 
 
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Elite in Gliosarcoma
Elite in Gliosarcoma
Referral may be required

Egil And Pauline Braathen Center/Maroone Cancer Center

2950 Cleveland Clinic Boulevard, 
Weston, FL 
877-463-2010
Languages Spoken:
English, Hindi
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Offers Telehealth

Surabhi Ranjan is a Neurologist practicing medicine in Weston, Florida. Dr. Ranjan is rated as an Elite provider by MediFind in the treatment of Gliosarcoma. She is also highly rated in 24 other conditions, according to our data. Her clinical expertise encompasses Gliosarcoma, Metastatic Brain Tumor, Brain Tumor, and Glioma. Dr. Ranjan is board certified in American Board Of Psychiatry And Neurology, 2015.

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How do I prevent Gliosarcoma?
There is no known way to prevent gliosarcomas. However, if you develop any symptoms common to a gliosarcoma, it is recommended to make an appointment with your doctor to be properly diagnosed.
What are the latest Gliosarcoma Clinical Trials?
Phase I/II Study to Evaluate the Safety and Clinical Efficacy of Atezolizumab (Anti-PD-L1) in Combination With Cabozantinib in Patients With Recurrent Glioblastoma (rGBM)
Phase I/II Study to Evaluate the Safety and Clinical Efficacy of Atezolizumab (Anti-PD-L1) in Combination With Cabozantinib in Patients With Recurrent Glioblastoma (rGBM)
Who is this study for: Patients with Recurrent Gliosarcoma
Enrollment Status: Recruiting
Publish Date: June 11, 2026
Intervention Type: Drug, Biological
Study Drugs: Atezolizumab, Cabozantinib
Study Phase: Phase 1/Phase 2

Summary: This phase I/II trial tests the safety and side effects of atezolizumab in combination with cabozantinib and whether they work to shrink tumors in patients with glioblastoma that has come back (recurrent). Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Cabozan...

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Phase Ib Trial of ABBV-637 or ABBV-155 in Combination With ERAS-801 for Glioblastoma With Amplification of the Epidermal Growth Factor Receptor
Phase Ib Trial of ABBV-637 or ABBV-155 in Combination With ERAS-801 for Glioblastoma With Amplification of the Epidermal Growth Factor Receptor
Enrollment Status: Recruiting
Publish Date: June 10, 2026
Intervention Type: Drug, Radiation
Study Phase: Phase 1

Summary: The researchers are doing this study to find out whether the drugs ABBV-637 and ABBV-155 are safe treatments that cause few or mild side effects when given alone or in combination with ERAS-801 in people with recurrent GBM.

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What are some Advocacy Organizations?
keep-punching-brain-cancer

Keep Punching supports patients, healthcare providers, and researchers in their fight to prevent and eradicate brain cancer and minimize treatment-related side effects that may adversely impact function and comfort.