The Efficacy of Doxycycline Post Exposure Prophylaxis for Preventing Sexually Transmitted Diseases (Gonorrhea, Chlamydia, Syphilis) Among Men Who Have Sex With Men in Bangkok, Thailand.

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY

The objective of this research is to evaluate the efficacy and safety of doxycycline in MSM for preventing sexually transmitted infections (gonorrhea, chlamydia, and syphilis) in Thailand Participation in this study will last approximately 12 weeks and will include 2-3 clinic visits, along with 10-11 follow-up phone contacts over a period of 11 weeks.

Eligibility
Participation Requirements
Sex: Male
Minimum Age: 18 days
Maximum Age: 2 months
Healthy Volunteers: t
View:

• Biological male, aged not over 60 years

• Thai nationality

• Able to read, communicate, and understand the Thai language

• Men who have sex with men (MSM), aged 18 years or older and not over 60 years

• Having at least one of the following risk factors:

• A history of condomless sex, or condom failure (breakage, leakage, or slippage), via any sexual route with at least two sexual partners within the past 3 months

• A diagnosis of gonorrhea, chlamydia, or syphilis within the past 6 months

• Current use of HIV pre-exposure prophylaxis (PrEP)

• Willing and able to participate in study procedures (e.g., able to return to the clinic for scheduled testing for gonorrhea, chlamydia, and syphilis; able to complete doxycycline use records; and able to receive follow-up phone calls from the research team)

• Willing and able to provide written informed consent to participate in the study

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Locations
Other Locations
Thailand
Bangrak STIs Center
RECRUITING
Sathorn
Contact Information
Primary
Rossapnorn Kittiyaowamarn, MD
rossaphorn@gmail.com
+66814501066
Backup
Kittipoom Chinhiran, MD
x_destiny_war@hotmail.com
+66863583077
Time Frame
Start Date: 2025-10-06
Estimated Completion Date: 2027-05-31
Participants
Target number of participants: 400
Treatments
Experimental: DoxyPEP arm
Participants will receive DoxyPEP for STIs prophylaxis in this arm
No_intervention: Control arm
Participants will receive standard STIs prevention
Related Therapeutic Areas
Sponsors
Collaborators: Mahidol University
Leads: Bangrak STIs Center

This content was sourced from clinicaltrials.gov