Gumma Overview
Learn About Gumma
A gumma is a soft, tumor-like growth of the tissues (granuloma) that occurs in people with syphilis.
A gumma is caused by the bacteria that cause syphilis. It appears during late-stage tertiary syphilis. It most often contains a mass of dead and swollen fiber-like tissue. It is most often seen in the liver. It also can occur in the:
- Bone
- Brain
- Heart
- Skin
- Testicles
- Eyes
Similar-looking sores sometimes occur with tuberculosis.
Hideyuki Akaza practices in Tokyo, Japan. Akaza is rated as an Elite expert by MediFind in the treatment of Gumma. Their top areas of expertise are Gumma, Prostate Cancer, Renal Cell Carcinoma (RCC), Orchiectomy, and Prostatectomy.
Ayako Sakamoto practices in Takasaki, Japan. Ms. Sakamoto is rated as an Elite expert by MediFind in the treatment of Gumma. Her top area of expertise is Gumma.
Iu Health Medical Group LLC
Melissa Ko is a Neurologist and an Ophthalmologist in Indianapolis, Indiana. Dr. Ko is rated as an Advanced provider by MediFind in the treatment of Gumma. Her top areas of expertise are Pseudotumor Cerebri Syndrome, Increased Intracranial Pressure, Meningitis, and Papilledema. Dr. Ko is currently accepting new patients.
Published Date: August 05, 2025
Published By: Jatin M. Vyas, MD, PhD, Roy and Diana Vagelos Professor in Medicine, Columbia University Vagelos College of Physicians and Surgeons, Division of Infectious Diseases, Department of Medicine, New York, NY. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Centers for Disease Control and Prevention website. Sexually transmitted infections treatment guidelines, 2021. www.cdc.gov/std/treatment-guidelines/default.htm. Updated June 13, 2023. Accessed August 21, 2025.
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Radolf JD, Salazar JC. Syphilis (Treponema pallidum). In: Blaser MJ, Cohen JI, Holland SM, et al, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 10th ed. Philadelphia, PA: Elsevier; 2026:chap 243.
Stary G, Stary A. Sexually transmitted infections. In: Bolognia JL, Schaffer JV, Cerroni L, eds. Dermatology. 5th ed. Philadelphia, PA: Elsevier; 2025:chap 82.