GummaSymptoms, Doctors, Treatments, Advances & More
Learn About Gumma
A gumma is a soft, tumor-like growth of the tissues (granuloma) that occurs in people with syphilis.
A gumma is caused by the bacteria that cause syphilis. It appears during late-stage tertiary syphilis. It most often contains a mass of dead and swollen fiber-like tissue. It is most often seen in the liver. It also can occur in the:
- Bone
- Brain
- Heart
- Skin
- Testicles
- Eyes
Similar-looking sores sometimes occur with tuberculosis.
Hideyuki Akaza practices practicing medicine in Tokyo, Japan. Akaza is rated as an Elite expert by MediFind in the treatment of Gumma. They are also highly rated in 4 other conditions, according to our data. Their clinical expertise encompasses Gumma, Prostate Cancer, Renal Cell Carcinoma (RCC), Orchiectomy, and Prostatectomy.
Ayako Sakamoto practices practicing medicine in Kokuryo, Japan. Ms. Sakamoto is rated as an Elite expert by MediFind in the treatment of Gumma. She is also highly rated in 1 other condition, according to our data. Her clinical expertise encompasses Gumma.
Advocate Medical Group Neurology
Timothy Mikesell is a Neurologist practicing medicine in Park Ridge, Illinois. Dr. Mikesell is rated as an Experienced provider by MediFind in the treatment of Gumma. His clinical expertise encompasses Gumma, Movement Disorders, Parkinson's Disease, and Memory Loss. Dr. Mikesell is board certified in American Board Of Psychiatry & Neurology, Vascular Neurology.
Published Date: August 05, 2025
Published By: Jatin M. Vyas, MD, PhD, Roy and Diana Vagelos Professor in Medicine, Columbia University Vagelos College of Physicians and Surgeons, Division of Infectious Diseases, Department of Medicine, New York, NY. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Centers for Disease Control and Prevention website. Sexually transmitted infections treatment guidelines, 2021. www.cdc.gov/std/treatment-guidelines/default.htm. Updated June 13, 2023. Accessed August 21, 2025.
Dinulos JGH. Sexually transmitted bacterial infections. In: Dinulos JGH, ed. Habif's Clinical Dermatology. 7th ed. Philadelphia, PA: Elsevier; 2021:chap 10.
Dionne JA, Ghanem KG. Syphilis and nonsyphilitic treponematoses. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 295.
Radolf JD, Salazar JC. Syphilis (Treponema pallidum). In: Blaser MJ, Cohen JI, Holland SM, et al, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 10th ed. Philadelphia, PA: Elsevier; 2026:chap 243.
Stary G, Stary A. Sexually transmitted infections. In: Bolognia JL, Schaffer JV, Cerroni L, eds. Dermatology. 5th ed. Philadelphia, PA: Elsevier; 2025:chap 82.