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A Prospective, Multicenter, Single-arm Clinical Investigation of the Safety and Performance of the Sentio System in a Pediatric Population

Status: Recruiting
Location: See all (8) locations...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study is performed to collect safety and performance data supporting the use of the Sentio system in children below 12 years of age. The system is currently available on the market for patients 12 years and above. It is a prospective study conducted at eight European hospitals, aiming to treat 50 patients with a hearing loss than would benefit from treatment with a bone-anchored hearing system (BAHS). The primary objective of the study is to demonstrate that the Sentio system improves the hearing on the implanted ear, compared with the unaided situation.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 3
Maximum Age: 11
Healthy Volunteers: f
View:

• Signed Informed Consent Form (depending on age of child, signed by parent or legal guardian and child)

• Subject aged 3 to 11 years

• Subject with:

⁃ 1 conductive or mixed hearing losses with pure tone average (PTA) bone conduction (BC) threshold (measured at 0.5, 1, 2 and 3 kHz) of the indicated ear better than or equal to 45 dB HL.

⁃ 2 OR subject who has a profound sensorineural hearing loss in one ear and normal hearing in the opposite ear (i.e. SSD). The pure tone average (PTA) air conduction (AC) threshold of the hearing ear should then be better than or equal to 20 dB HL (measured at 0.5, 1, 2 and 3 kHz) 3.3 OR subject indicated for an air-conduction contralateral routing of signals (AC CROS) hearing aid, but who for some reason cannot or will not use an AC CROS.

• Subject and parent or legal guardian have the ability and willingness to comply with investigational procedures/ requirements, as determined by the investigator.

• Subject with prior experience of amplified sound through a properly fitted hearing aid, a CROS device, or a non-surgical bone anchored solution (e.g. softband).

• For subject with conductive or mixed hearing losses, ensure sufficient air bone gap (ABG) at the ear to be implanted.

• Sufficient bone quality/quantity/depth or skull size for implantation of a Sentio Ti implant as assessed according to clinical practice.

Locations
Other Locations
Netherlands
University Medical Center Groningen
RECRUITING
Groningen
Radboud University Medical Center
RECRUITING
Nijmegen
Spain
Hospital Universitario de Donostia
RECRUITING
San Sebastián
Hospital Universitario Virgen Macarena
RECRUITING
Seville
Hospital Universitario y Politécnico La Fe
RECRUITING
Valencia
United Kingdom
Birmingham Children's hospital, Birmingham Women's and Children's NHS Foundation Trust
RECRUITING
Birmingham
Great Ormond Street Hospital, Great Ormond Street Hospital for Children NHS Foundation Trust
RECRUITING
London
The Evelina London Children's Hospital, Guy's and St Thomas' NHS Foundation Trust
RECRUITING
London
Contact Information
Primary
Sara Svensson, MSc, PhD
ssve@oticonmedical.com
+46 73 504 2041
Backup
Marianne Philipsson, MSc
maph@oticonmedical.com
+46 70 098 1715
Time Frame
Start Date: 2025-04-30
Estimated Completion Date: 2027-07-01
Participants
Target number of participants: 50
Treatments
Experimental: Sentio system
Prospective, open label, single-arm multicentre investigation designed to follow clinical practice for bone conduction devices.
Related Therapeutic Areas
Sponsors
Collaborators: Great Ormond Street Hospital for Children NHS Foundation Trust, University Medical Center Groningen, Hospital Universitario La Fe, Hospital Donostia, Guy's and St Thomas' NHS Foundation Trust, Birmingham Women's and Children's NHS Foundation Trust, Radboud University Medical Center, Hospital Universitario Virgen Macarena
Leads: Oticon Medical

This content was sourced from clinicaltrials.gov