Assessing the Relationship Between Myonectin Concentration and the Course of Hospitalization and the 30-day Risk of Cardiac Endpoints in Patients With the First Incident of ST-segment Elevation Mycardial Infarction Treated With Primary PCI

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The aim of this study is to test the potentially protective role of myonectin in patients with a first episode of ST elevation myocardial infarction (MI) treated with primary percutaneous coronary intervention (PCI). The main questions which are assumed to be answered after study completion: 1. Does higher myonectin concentration influence the in-hospital and 30-day course of the first ST-elevation MI in patients treated with primary coronary angioplasty 2. Is there a relationship between the serum myonectin concentration, related to patient's nutritional status and physical activity with the patient's physical activity declared as usually before the coronary event occurrence, the cardiac biomarkers level, and myocardial and skeletal muscle mass determined in order to objectify the relationship of physical activity before the infarction with 30-day and one-year mortality, and the other primary and secondary outcomes measured at 12-month visit, e.g. the extent of myocardial infarction, 3. Is there a relationship between the baseline concentration of myonectin and troponin with the control of atherosclerosis risk factors, declared physical activity and parameters of body composition, outcome of treadmill exercise test, values of echocardiographic parameters and myonectin concentration 12 months after a cardiovascular incident

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• symptoms of acute coronary syndrome

• acute ST segment elevation in two or more leads in ECG

• primary PCI

Locations
Other Locations
Poland
Voivodeship Hospital in Elblag
RECRUITING
Elblag
Contact Information
Primary
Michał Jaśkiewicz, MD
mich.jask@gmail.com
+48 606613129
Time Frame
Start Date: 2023-01-01
Estimated Completion Date: 2026-05-31
Participants
Target number of participants: 100
Sponsors
Collaborators: Jan Biziel University Hospital No 2 in Bydgoszcz
Leads: Michał Jaśkiewicz

This content was sourced from clinicaltrials.gov