Mini-Crush Or Controlled Balloon-Crush For True Coronary Bifurcation Lesions

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

The mini-crush technique is one of the leading 2-stent techniques frequently applied by interventional cardiologists to treat complex bifurcation lesions. In the last 20 years, many technical innovations and iterations of mini-crush technique have been developed, and it maintains its popularity among invasive cardiologists. Moreover, mini-crush and double kissing-crush techniques have been compared in terms of clinical results in both left main and non-left main coronary bifurcation patient populations and no significant difference was found. However, the most important challenges of the mini-crush technique are the rewiring and advancement of a 1:1 non-compliant side-branch balloon after the main branch stent has been implanted. These challenges usually necessitate the use of a low profile balloon or additional support maneuvers (such as anchor balloon). Recently, a novel modified mini-crush-crush technique (controlled balloon-crush) has been introduced to the literature and is one of the most up-to-date crush techniques. The main advantage of this technique over the contemporary mini-crush technique is that the side branch can be easily rewired and the 1:1 size non-compliant balloon can easily pass through the crushed stent structure in the ostial part of the side branch. The basic rationale of this is that the crushing of the side branch stent is done in a more controlled manner (by slowly deflation of the side branch stent balloon) and this causes less disruption of the stent cells. This prospective observational study aims to assess the procedural and 1-year clinical outcomes of the contemporary mini-crush and controlled balloon-crush (modified mini-crush) double stenting techniques in patients with true coronary bifurcation lesions.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Aged \>18

• PCI with mini-crush or controlled balloon-crush

• Complex coronary bifurcation lesion (Medina 0.1.1 and Medina 1.1.1)

Locations
Other Locations
Turkey
Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital
RECRUITING
Istanbul
Contact Information
Primary
Fatih Uzun, Professor
fatihuzun28@gmail.com
+90 5057705766
Backup
Ahmet Güner, MD
ahmetguner488@gmail.com
+90 2126922000
Time Frame
Start Date: 2025-03-03
Estimated Completion Date: 2026-08-01
Participants
Target number of participants: 400
Treatments
Mini-crush stenting Group
Stenting with mini-crush technique for true coronary bifurcation lesions
Controlled balloon-crush Group
Stenting with controlled balloon-crush technique for true coronary bifurcation lesions
Related Therapeutic Areas
Sponsors
Collaborators: Istanbul Medipol University Hospital, Trakya University, Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital, Cigli Regional Training Hospital, Başakşehir Çam & Sakura City Hospital, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Ankara City Hospital Bilkent, Sisli Hamidiye Etfal Training and Research Hospital, Ankara Etlik City Hospital, İstanbul Bağcılar Training and Research Hospital, Istanbul University - Cerrahpasa
Leads: Istanbul Mehmet Akif Ersoy Educational and Training Hospital

This content was sourced from clinicaltrials.gov