Heart Failure with Preserved Ejection Fraction (HFpEF)
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Heart Failure with Preserved Ejection Fraction (HFpEF) Overview

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Learn About Heart Failure with Preserved Ejection Fraction (HFpEF)

What is the definition of Heart Failure with Preserved Ejection Fraction (HFpEF)?
Heart failure with preserved ejection fraction is a syndrome wherein the left ventricle of the heart is unable to relax normally between each heartbeat. This leads to an increase in blood pressure in the left ventricle when blood fills it between each heartbeat. An ejection fraction measures how well the heart pumps blood. In heart failure with preserved ejection fraction, while there is heart failure the ejection fraction is normal.
What are the symptoms of Heart Failure with Preserved Ejection Fraction (HFpEF)?
Symptoms of heart failure with preserved ejection fraction include shortness of breath, especially when lying flat; chest discomfort; fatigue; exercise intolerance; abdominal swelling; and lower leg swelling.
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What are the current treatments for Heart Failure with Preserved Ejection Fraction (HFpEF)?
Treatment for heart failure with preserved ejection fraction includes treating high blood pressure with medications, diuretics, and cardiac revascularization.
Who are the top Heart Failure with Preserved Ejection Fraction (HFpEF) Local Doctors?
Sanjiv J. Shah
Elite in Heart Failure with Preserved Ejection Fraction (HFpEF)
Elite in Heart Failure with Preserved Ejection Fraction (HFpEF)
675 N St Clair St Ste 19-100, Galter Pavilion, 
Chicago, IL 
Experience:
26+ years
Languages Spoken:
English
Offers Telehealth

Sanjiv Shah is a Cardiologist in Chicago, Illinois. Dr. Shah has been practicing medicine for over 26 years and is rated as an Elite provider by MediFind in the treatment of Heart Failure with Preserved Ejection Fraction (HFpEF). His top areas of expertise are Heart Failure with Preserved Ejection Fraction (HFpEF), Heart Failure, Cardiac Amyloidosis, Cardiac Ablation, and Heart Transplant.

Scott D. Solomon
Elite in Heart Failure with Preserved Ejection Fraction (HFpEF)
Elite in Heart Failure with Preserved Ejection Fraction (HFpEF)

Brigham And Women's Hospital, Heart And Vascular Center

70 Francis Street, Carl J. And Ruth Shapiro Cardiovascular Center, 
Boston, MA 
Languages Spoken:
English

Scott Solomon is a Cardiologist in Boston, Massachusetts. Dr. Solomon is rated as an Elite provider by MediFind in the treatment of Heart Failure with Preserved Ejection Fraction (HFpEF). His top areas of expertise are Heart Failure with Preserved Ejection Fraction (HFpEF), Heart Failure, Atherosclerosis, Heart Bypass Surgery, and Pacemaker Implantation.

 
 
 
 
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Muthiah Vaduganathan
Elite in Heart Failure with Preserved Ejection Fraction (HFpEF)
Elite in Heart Failure with Preserved Ejection Fraction (HFpEF)

Brigham And Women's Hospital, Heart And Vascular Center

70 Francis Street, Carl J. And Ruth Shapiro Cardiovascular Center, 
Boston, MA 
Languages Spoken:
English

Dr. Vaduganathan is a cardiologist at Brigham and Women’s Hospital and faculty at Harvard Medical School. He received his medical doctorate and a Master of Public Health degree from Northwestern University. He subsequently completed his residency training in Internal Medicine at Massachusetts General Hospital and fellowship training in Cardiovascular Medicine at Brigham and Women’s Hospital. Dr. Vaduganathan is board certified in internal medicine and cardiovascular disease.Dr. Vaduganathan’s clinical interests surround the intersection between diabetes mellitus, obesity, and heart disease. The author of over 250 peer-reviewed publications, his research focuses on drug development and clinical trials of cardiometabolic therapies. Dr. Vaduganathan is rated as an Elite provider by MediFind in the treatment of Heart Failure with Preserved Ejection Fraction (HFpEF). His top areas of expertise are Heart Failure, Heart Failure with Preserved Ejection Fraction (HFpEF), Heart Attack, Percutaneous Coronary Intervention (PCI), and Heart Transplant.

What are the latest Heart Failure with Preserved Ejection Fraction (HFpEF) Clinical Trials?
A Phase 2, Multicenter, Double-blind, Extension Study to Evaluate the Effects of Sotatercept for the Treatment of Combined Postcapillary and Precapillary Pulmonary Hypertension (Cpc-PH) Due to Heart Failure With Preserved Ejection Fraction (HFpEF)

Summary: Researchers are looking for new ways to treat people with a type of pulmonary hypertension called combined postcapillary and precapillary pulmonary hypertension (Cpc-PH). This study focuses on Cpc-PH that is caused by heart failure with preserved ejection fraction (HFpEF). Researchers want to know if the study treatment, sotatercept, can treat people with Cpc-PH caused by HFpEF. This is an extensi...

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A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Maridebart Cafraglutide on Mortality and Morbidity in Participants Living With Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity (MARITIME-HF)

Summary: This trial will examine if maridebart cafraglutide as an adjunct to standard of care will lead to a reduction in heart failure (HF) events such as HF hospitalizations and urgent HF visits, cardiovascular (CV) deaths and improvement in HF symptoms in participants with HF with preserved ejection fraction (HFpEF) and HF with mildly reduced ejection fraction (HFmrEF) who are obese. This is a phase 3, ...