Heart Failure with Preserved Ejection Fraction (HFpEF)
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Heart Failure with Preserved Ejection Fraction (HFpEF) Overview

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Learn About Heart Failure with Preserved Ejection Fraction (HFpEF)

What is the definition of Heart Failure with Preserved Ejection Fraction (HFpEF)?
Heart failure with preserved ejection fraction is a syndrome wherein the left ventricle of the heart is unable to relax normally between each heartbeat. This leads to an increase in blood pressure in the left ventricle when blood fills it between each heartbeat. An ejection fraction measures how well the heart pumps blood. In heart failure with preserved ejection fraction, while there is heart failure the ejection fraction is normal.
What are the symptoms of Heart Failure with Preserved Ejection Fraction (HFpEF)?
Symptoms of heart failure with preserved ejection fraction include shortness of breath, especially when lying flat; chest discomfort; fatigue; exercise intolerance; abdominal swelling; and lower leg swelling.
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What are the current treatments for Heart Failure with Preserved Ejection Fraction (HFpEF)?
Treatment for heart failure with preserved ejection fraction includes treating high blood pressure with medications, diuretics, and cardiac revascularization.
Who are the top Heart Failure with Preserved Ejection Fraction (HFpEF) Local Doctors?
Elite in Heart Failure with Preserved Ejection Fraction (HFpEF)
Elite in Heart Failure with Preserved Ejection Fraction (HFpEF)

Brigham And Women's Hospital, Heart And Vascular Center

70 Francis Street, Carl J. And Ruth Shapiro Cardiovascular Center, 
Boston, MA 
Languages Spoken:
English

Dr. Vaduganathan is a cardiologist at Brigham and Women’s Hospital and faculty at Harvard Medical School. He received his medical doctorate and a Master of Public Health degree from Northwestern University. He subsequently completed his residency training in Internal Medicine at Massachusetts General Hospital and fellowship training in Cardiovascular Medicine at Brigham and Women’s Hospital. Dr. Vaduganathan is board certified in internal medicine and cardiovascular disease.Dr. Vaduganathan’s clinical interests surround the intersection between diabetes mellitus, obesity, and heart disease. The author of over 250 peer-reviewed publications, his research focuses on drug development and clinical trials of cardiometabolic therapies. Dr. Vaduganathan is rated as an Elite provider by MediFind in the treatment of Heart Failure with Preserved Ejection Fraction (HFpEF). He is also highly rated in 16 other conditions, according to our data. His clinical expertise encompasses Heart Failure, Heart Failure with Preserved Ejection Fraction (HFpEF), Heart Attack, Percutaneous Coronary Intervention (PCI), and Heart Transplant. Dr. Vaduganathan is board certified in Internal Medicine and Cardiovascular Disease.

Elite in Heart Failure with Preserved Ejection Fraction (HFpEF)
Transplant Surgery
Elite in Heart Failure with Preserved Ejection Fraction (HFpEF)
Transplant Surgery

MUSC Health Cardiology At Ashley River Tower

25 Courtenay Drive, 1st Floor, 
Charleston, SC 
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Dr. Zile is a graduate of Rush University School of Medicine. He did his internal medicine residency at Rush Presbyterian St. Lukes Medical Center in Chicago, a clinical cardiology fellowship at Tufts-New England Medical Center in Boston and a research cardiology fellowship at the Department of Veterans Affairs Medical Center, Boston. Dr. Zile is currently the Charles Ezra Daniel professor of medicine at the Medical University of South Carolina.He also serves as the director of cardiology at the Ralph H. Johnson Department of Veteran's Affairs Medical Center in Charleston. He is an adjunct professor of bioengineering at Clemson University.Dr. Zile's research career has involved both basic laboratory research examining the mechanisms of disease development and progression and translational clinical research examining the application of these basic mechanisms to development of effective treatment methods.Dr. Zile is a recognized leader in the areas of cardiac function, congestive heart failure, diastolic heart failure and valvular heart disease. His research is supported by grants from the National Heart, Lung and Blood Institute, the American Heart Association, the Department of Veterans Affairs and the Medical University of South Carolina.Dr. Zile is the author of over 100 peer-reviewed publications. He is a member of a number of professional societies including the American College of Physicians, American Federation of Clinical Research, American Heart Association, American College of Cardiology, the Heart Failure Society of America, International Society of Heart Failure, and the American Physiology Society. Dr. Zile has served on the research, educational and program committees of these organizations. He serves on the editorial boards of the Journal of the American College of Cardiology and Circulation and is an editorial consultant to a number of others including Circulation Research, Journal of Clinical Investigation and the American Journal of Physiology. Dr. Zile is a member of the Association of University Cardiologists and a member of the ABIM Subspecialty Board on Cardiovascular Disease. Dr. Zile is rated as an Elite provider by MediFind in the treatment of Heart Failure with Preserved Ejection Fraction (HFpEF). He is also highly rated in 14 other conditions, according to our data. His clinical expertise encompasses Heart Failure, Heart Failure with Preserved Ejection Fraction (HFpEF), Hypertensive Heart Disease, Pacemaker Implantation, and Cardiac Ablation. Dr. Zile is currently accepting new patients.

 
 
 
 
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Elite in Heart Failure with Preserved Ejection Fraction (HFpEF)
Elite in Heart Failure with Preserved Ejection Fraction (HFpEF)

Atrium Health Wake Forest Baptist

S Hawthorne Rd, 
Winston Salem, NC 
Languages Spoken:
English

Dalane Kitzman is a Cardiologist practicing medicine in Winston Salem, North Carolina. Dr. Kitzman is rated as an Elite provider by MediFind in the treatment of Heart Failure with Preserved Ejection Fraction (HFpEF). He is also highly rated in 6 other conditions, according to our data. His clinical expertise encompasses Heart Failure with Preserved Ejection Fraction (HFpEF), Heart Failure, Atherosclerosis, and Cardiomyopathy.

What are the latest Heart Failure with Preserved Ejection Fraction (HFpEF) Clinical Trials?
SGLT2i and KNO3 in HFpEF - The SAK HFpEF Trial

Summary: This study will test whether pharmacologic agents that may improve mitochondrial function and energy fuel metabolism \[Empagliflozin (Empa)\], with and without additional supplements that increase perfusion and fatty acid oxidation \[Potassium Nitrate (KNO3)\], improve submaximal exercise endurance and skeletal muscle oxidative phosphorylation capacity (SkM OxPhos) in participants with Heart Failu...

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A Phase 3 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Maridebart Cafraglutide on Mortality and Morbidity in Participants Living With Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity (MARITIME-HF)

Summary: This trial will examine if maridebart cafraglutide as an adjunct to standard of care will lead to a reduction in heart failure (HF) events such as HF hospitalizations and urgent HF visits, cardiovascular (CV) deaths and improvement in HF symptoms in participants with HF with preserved ejection fraction (HFpEF) and HF with mildly reduced ejection fraction (HFmrEF) who are obese. This is a phase 3, ...