Arterial Stiffening as a Predictor for Diastolic Cardiac Dysfunction and HFpEF
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
Patients at risk for developing heart failure with preserved ejection fraction (HFpEF) will undergo a structured clinical assessment, transthoracic echocardiography and pulse-wave analysis to investigate the association of arterial stiffening and the development of cardiac diastolic dysfuntion and HFpEF.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
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⁃ One or more of the following criteria:
• Age \> 60 years
• Arterial hypertension (RR systolic ≥ 140 mmHg or diastolic ≥ 90 mmHg or ≥ 2 antihypertensive drugs)
• Diabetes mellitus Type I or II
• Atrial fibrillation
• Chronic kidney disease (GFR \< 60 ml/min/1,73 m2 or urine albumin ≥ 30mg/24h or ACR ≥ 30 mg/g)
• BMI ≥ 30 kg/m2
• NYHA ≥ II
• E/e' \> 8
Locations
Other Locations
Germany
Universitätsmedizin Göttingen
RECRUITING
Göttingen
Time Frame
Start Date: 2024-02-23
Estimated Completion Date: 2028-01
Participants
Target number of participants: 150
Related Therapeutic Areas
Sponsors
Leads: University Medical Center Goettingen