Distribution and Clinical Implication of Coronary Flow Reserve and Index of Microcirculatory Resistance in Patients With Heart Failure With Preserved Ejection Fraction Without Significant Coronary Artery Disease
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY
To evaluate the incidence of coronary microvascular dysfunction (CMD) and its' prognostic implication in patients who have diagnosed as heart failure with preserved ejection fraction (HFpEF) confirmed by HFA-PEFF scoring system without functionally significant coronary artery disease.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 19
Healthy Volunteers: f
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• Subject must be at least 19 years of age.
• Subject with preserved ejection fraction (ejection fraction \> 50%)
• Subject presented with dyspnea on exertion (NYHA Grade 2 or more) and diagnosed as HFpEF using HFA-PEFF scoring system (HFA-PEFF ≥5 or 2-4 with abnormal stress test or invasive hemodynamic test)
• Subject who clinically need coronary angiography
• Subject who is able to voluntarily sign informed consent form
Locations
Other Locations
Republic of Korea
Samsung Medical Center
RECRUITING
Seoul
Contact Information
Primary
Ki Hong Choi, MD
cardiokh@gmail.com
82-2-3410-1246
Time Frame
Start Date: 2021-01-25
Estimated Completion Date: 2024-12-31
Participants
Target number of participants: 100
Treatments
Patients with heart failure with preserved ejection fraction (HFpEF)
Subject with preserved ejection fraction (ejection fraction \> 50%) and with dyspnea on exertion (NYHA Grade 2 or more) and diagnosed as HFpEF using HFA-PEFF scoring system (HFA-PEFF ≥5 or 2-4 with abnormal stress test or invasive hemodynamic test)
Related Therapeutic Areas
Sponsors
Leads: Samsung Medical Center