The Role of Epicardial Adiposity in Heart Failure With Preserved Ejection Fraction

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

In this study the investigators are aiming to recruit 130 patients with heart failure with preserved ejection fraction who are obese and non-obese to undergo CT and MRI scans, as well as some other investigations including blood tests, to help investigate if having more fat around the heart leads to worse heart function in this condition. This may lead to the development of new treatments aimed at lowering fat levels around the heart and in the rest of the body, specifically to treat HFpEF.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Participant is willing and able to give informed consent for participation in the study.

• Aged ≥18 years old

• Diagnosed with HFpEF and diagnosis confirmed by an experienced cardiologist using the HFA-PEFF diagnostic algorithm

• Echocardiogram performed within 12 months

• Able to understand written English

Locations
Other Locations
United Kingdom
Glenfield Hospital, University Hospitals of Leicester
RECRUITING
Leicester
Contact Information
Primary
Gaurav S Gulsin, MBChB(Hons)
gg149@le.ac.uk
+44 (0)116 258 3038
Backup
Sarah L Ayton, MBBS
sa768@le.ac.uk
Time Frame
Start Date: 2025-02-12
Estimated Completion Date: 2037-08
Participants
Target number of participants: 130
Treatments
Participants with HFpEF
Obese and non-obese participants with heart failure with preserved ejection fraction
Sponsors
Leads: University of Leicester

This content was sourced from clinicaltrials.gov

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