CATCH-HF: Cardiotoxicity Assessment Through Comprehensive Heart Imaging to Predict Heart Failure

Status: Recruiting
Location: See location...
Intervention Type: Other, Diagnostic test
Study Type: Observational
SUMMARY

Anthracycline chemotherapies (e.g. doxorubicin, daunorubicin) are commonly given to treat pediatric cancer, and carry a risk of cardiotoxicity. Over the long term, children who receive these therapies have an increased risk of heart failure and early cardiovascular death. However, current strategies for identifying patients who are at risk prior to the development of significant changes in heart function are limited. This study will focus on imaging markers of cardiac injury and dysfunction with the goal of developing improved diagnostic tests and treatment strategies.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 13
Maximum Age: 39
Healthy Volunteers: f
View:

• English and Spanish speaking male and female subjects, ages 13-39 years old

• Diagnosis of cancer at age \<22 years

• Previously treated with anthracyline therapy for cancer, with diagnosis at least two years prior.

Locations
United States
California
Rady Children's Hospital
RECRUITING
San Diego
Contact Information
Primary
Hari Narayan, MD
hnarayan@rchsd.org
8589665855 / 8589331718
Backup
Cesar Vasquez
cvasquez2@rchsd.org
8589331718
Time Frame
Start Date: 2019-09-30
Estimated Completion Date: 2030-09-30
Participants
Target number of participants: 150
Treatments
All Study Participants
This is an observational study where all study participants are within a single group.~Participants will have testing performed at baseline and again at follow-up \>= 3 years after the initial assessment.
Authors
Danica Griffin, Albert Hsiao, Erin Trovillion
Related Therapeutic Areas
Sponsors
Leads: Hari Narayan

This content was sourced from clinicaltrials.gov