Tracking Atrial Fibrillation After Intensive Care Admission

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY

Atrial fibrillation (AF) is a heart problem that causes an irregular heartbeat. It can cause the heart to beat more rapidly and reduce the heart's ability to pump blood around the body efficiently, causing heart failure. It also increases the risk of blood clots forming inside the heart. These clots may then be pumped out of the heart, through the blood vessels, to other parts of the body. This can cause strokes if the clots spread to the brain. AF is a common problem outside an Intensive Care Unit (ICU), where treatment is based on good, evidence-based guidelines designed to reduce the risk of problems like heart failure or strokes. Around 10% of patients treated in ICU develop atrial fibrillation as a complication of their underlying illness. Some patients will recover their normal heart rhythm before leaving the ICU, often with the help of some medical treatments. It is not known whether these patients will get AF again after leaving the ICU, or when this is likely to happen. It is also unknown whether patients who avoid AF whilst on the ICU may still be at high risk of developing it after they leave. This study will identify patients on the ICU who have no previous record of atrial fibrillation. These patients will be monitored whilst on the ICU to identify those who develop AF. Those patients who develop new onset AF will be monitored on the ward after leaving the ICU to see which patients have AF at this point. The heart monitoring will be repeated once the patients leave hospital, again to identify whether they have atrial fibrillation. Some studies suggest that AF during critical illness causes a long-term risk of recurrent AF and AF associated complications such as heart failure, stroke, and death. To understand how to minimise these risks in intensive care patients, we need to know how which patients who develop atrial fibrillation whilst in an ICU go on to have recurrent atrial fibrillation in hospital and in the community. These patients may benefit from interventions to reduce long term adverse events such as anticoagulation to reduce stroke risk.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 16
View:

• Willing and able to give informed consent for participation in the study, or favourable consultee advice for adults lacking capacity

• Male or Female,

• aged 16 years or above.

• Admitted to intensive care for \>24 hours

• New onset atrial fibrillation as confirmed by 12 lead ECG-

Locations
Other Locations
United Kingdom
Oxford University Hospitals Trust
RECRUITING
Oxford
Contact Information
Primary
Peter Watkinson, MD.
ccrg.research@ndcn.ox.ac.uk@ndcn.ox.ac.uk
01865231448
Backup
Rachel Henning
ccrg.research@ndcn.ox.ac.uk
01865231448
Time Frame
Start Date: 2022-02-01
Estimated Completion Date: 2025-12-30
Participants
Target number of participants: 100
Treatments
New Onset Atrial Fibrillation
Patients admitted to an adult intensive care unit for more than 24 hours who develop new onset atrial fibrillation during their ICU admission will be included. After discharge from ICU patients will undergo continuous ECG monitoring via VitalConnect patch for 14 days or until hospital discharge, whichever is shortest. They will undergo a further 7 days of continuous ECG monitoring via VitalConnect patch as an outpatient at 3 months post hospital discharge.
Sponsors
Leads: University of Oxford

This content was sourced from clinicaltrials.gov