Cardiac Computed Tomography for Comprehensive Risk Stratification of Arrhythmic, Atherothrombotic and Heart Failure Events Following Reperfused ST-segment Elevation Myocardial Infarction

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The CT-STEMI study aims to evaluate a comprehensive cardiac computed tomography (CCT) protocol for assessing the risk of heart failure (HF), life-threatening arrhythmias (LTA), and atherothrombotic events following ST-elevation myocardial infarction (STEMI). This multicenter, prospective study has three main objectives: 1. Comparing the diagnostic accuracy of the comprehensive CCT protocol with cardiac magnetic resonance (CMR), considered the non-invasive gold standard. 2. Determining the prognostic value of CCT in assessing myocardial tissue adverse features related to STEMI. 3. Evaluating the atherosclerotic burden in patients with post-acute STEMI. Two hundred patients will undergo both CCT and CMR in the post-acute phase, and their follow-up will focus on monitoring HF, LTA, and ischemic events. The CT-STEMI study represents the first attempt to assess the potential of CCT in providing a comprehensive risk assessment following STEMI in a large contemporary population. The findings of this study have the potential to revolutionize post-STEMI risk stratification practices.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Signed informed consent

• STEMI diagnosis

• Primary Percutaneous Coronary Intervention (PCI) \<24h from symptom onset

• Hemodynamic stability without inotropic support within 4 days from the index event

Locations
Other Locations
Italy
Azienda Ospedaliera Policlinico Universitario G. Martino
RECRUITING
Messina
Istituto Auxologico Italiano - IRCCS - Ospedale San Luca
RECRUITING
Milan
A.O.U. Città della Salute e della Scienza - Molinette Hospital
RECRUITING
Turin
Contact Information
Primary
Marco Gatti, M.D.
m.gatti@unito.it
+390116334175
Time Frame
Start Date: 2023-11-08
Estimated Completion Date: 2026-04-30
Participants
Target number of participants: 200
Treatments
Experimental: STEMI patients
Patients with reperfused ST-segment Elevation Myocardial Infarction
Related Therapeutic Areas
Sponsors
Leads: University of Turin, Italy
Collaborators: University of Messina, Istituto Auxologico Italiano, Ministry of Health, Italy, A.O.U. Città della Salute e della Scienza - Molinette Hospital

This content was sourced from clinicaltrials.gov