Clinical Study on the 2C3L Strategy Based on Marshall Venous Chemoablation for the Treatment of Persistent Atrial Fibrillation Combined With Heart Failure

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

(1) To evaluate the efficacy and safety of 2C3L strategy combined with VOM anhydrous ethanol chemical ablation for persistent atrial fibrillation complicated with heart failure; (2) To evaluate the effectiveness of high-efficiency ablation of atrial fibrillation complicated with heart failure.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:

• age:18y-80y

• First ablation on non valvular atrial fibrillation

• Persistent atrial fibrillation with LVEF≤40%

• The patient has symptoms related to atrial fibrillation, including but not limited to palpitations, premonitory syncope, syncope, fatigue, and shortness of breath, and is evaluated for clinical cardiac function between NYHA II-IV levels

• No response to antiarrhythmic drugs, unacceptable side effects, or unwillingness to take antiarrhythmic drugs.

Locations
Other Locations
China
Hesheng Hu
RECRUITING
Jinan
Contact Information
Primary
Hesheng Hu
hyperhhs@163.com
13589112300
Backup
Xinran Li
xinran0207@126.com
17686619036
Time Frame
Start Date: 2022-06-16
Estimated Completion Date: 2025-06-16
Participants
Target number of participants: 130
Treatments
Sham_comparator: 2C3L group
Ablation Procedure:2C3L
Experimental: 2C3L-plus group
Ablation Procedure:2C3L combined with Marshall ethanol ablation
Related Therapeutic Areas
Sponsors
Leads: Qianfoshan Hospital

This content was sourced from clinicaltrials.gov