Inspiratory Muscle Training in Heart Failure With Preserved Ejection Fraction
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
This study is being done to determine how inspiratory muscle training impacts inspiratory muscle function during exercise in heart failure patients.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• ≥18 yrs of age
• Receiving SGLT2 inhibitors and spironolactone (and beta-blocker use for HFpEF patients with hypertension) for \>3 months
• NYHA symptoms I-III
• Body mass index ≤40 kg/m2
• Currently non-smokers with \<20 pack year history
• Able to exercise (i.e. without significant orthopedic limitations or musculoskeletal disorders limiting their ability to exercise)
Locations
United States
Minnesota
Mayo Clinic in Rochester
RECRUITING
Rochester
Contact Information
Primary
Eric Bruhn, M.A.
bruhn.eric@mayo.edu
507-266-2690
Time Frame
Start Date: 2024-10-09
Estimated Completion Date: 2028-04
Participants
Target number of participants: 68
Treatments
Experimental: Inspiratory muscle training (IMT) group
IMT performed at 40% maximal inspiratory pressure (MIP) for 30 minutes 7 days a week for 8 weeks.
Sham_comparator: SHAM group
IMT performed at 2% maximal inspiratory pressure (MIP) for 30 minutes 7 days a week for 8 weeks.
Related Therapeutic Areas
Sponsors
Leads: Mayo Clinic
Collaborators: National Heart, Lung, and Blood Institute (NHLBI)