AlEX-DHF: Ablation and Exercise in Diastolic Heart Failure
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The investigators analyze the impact of exercise and ablation in patients with symptomatic short-persistent atrial fibrillation (Afib) and heart failure with preserved ejection fraction (HFpEF). It is hypothesized that the combination of ablation and exercise better improves peak oxygen consumption (VO2peak) through improvement of peripheral (exercise training) and central (ablation) adaptations. Exercise intervention will contain a 12-week combined, video-based, supervised, endurance, resistance and respiratory training.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 99
Healthy Volunteers: f
View:
• Diagnosed heart failure with preserved ejection fraction
• Symptomatic short-persistent atrial fibrillation (diagnosis within 1 year of study inclusion)
Locations
Other Locations
Germany
Department of Medicine, Division of Prevention and Sports Medicine TU Munich
RECRUITING
Munich
Contact Information
Primary
Martin Halle, Professor
martin.halle@mri.tum.de
+49 8928924441
Backup
Manuel Rattka, MD
manuel.rattka@mri.tum.de
+49 8928924441
Time Frame
Start Date: 2026-02-01
Estimated Completion Date: 2027-06-30
Participants
Target number of participants: 40
Treatments
Experimental: Intervention Group
This group receives exercise training
No_intervention: Control Group
This group does not receive exercise training
Related Therapeutic Areas
Sponsors
Leads: Technical University of Munich