Association Between Vasopressor Exposure Levels and 30-Day Mortality in Patients Receiving ECMO Support for Cardiogenic Shock: A Prospective Multicenter Cohort Study
Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Observational
SUMMARY
The goal of this observational study is to learn about the association between vasopressor exposure levels and outcomes in adults with cardiogenic shock receiving VA-ECMO. The main question it aims to answer is: Does reduced exposure to vasopressors lower the 30-day mortality in patients with cardiogenic shock when receiving ECMO support? Participants who are receiving ECMO support for cardiogenic shock as part of their regular medical care will have their data collected, including information about their vasopressor use and mortality outcomes, over the course of the study.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Adults (≥18 years) with cardiogenic shock requiring VA-ECMO support.
• First-time ECMO initiation.
• Venoarterial ECMO (VA-ECMO) as the initial mode.
Locations
Other Locations
China
Beijing Anzhen Hospital
RECRUITING
Beijing
Contact Information
Primary
Xiaotong Hou, MD
xt.hou@ccmu.edu.cn
010-64456631
Backup
Chenglong Li, MD
cl_lee@163.com
86-18610846901
Time Frame
Start Date: 2025-02-26
Estimated Completion Date: 2028-01-01
Participants
Target number of participants: 534
Treatments
High VIS Group
High VIS Group: Patients with an average Vasoactive-Inotropic Score (VIS) \>10 from 12 hours post-ECMO initiation to weaning.
Low VIS Group
Low VIS Group: Patients with an average Vasoactive-Inotropic Score (VIS) ≤10 from 12 hours post-ECMO initiation to weaning.
Related Therapeutic Areas
Sponsors
Leads: Xiaotong Hou