Heart Failure Clinical Trials

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Digital Solutions in Heart Therapy (DIGNITY) - a Randomized Controlled Trial Using Telemedicine for Heart Failure Treatment

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study aims to assess the safety and effectiveness of telemedicine guided strategy on guideline-directed medical therapy (GDMT) optimization in hospitalized patients with heart failure in comparison to usual care in Switzerland.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Age \> 18 years at the time of hospital admission

• Ability to use a (smart)phone and/or tablet for the follow-up

• Documented left ventricular ejection fraction (LVEF) \> 40% assessed within preceding 12 months

• Not treated with optimal doses of oral HF therapies within 2 days before anticipated hospital discharge for acute HF in at least one of the medication categories (for details see Table 1 on page 10)

• Hospitalized due to acute HF decompensation.

• Specific measures within 24 hours prior to randomization

‣ Systolic blood pressure \> 100 mmHg, and heart rate \> 60bpm

⁃ Serum potassium \< 5mmol/L

Locations
Other Locations
Switzerland
University Hospital Basel
RECRUITING
Basel
Contact Information
Primary
Qian Zhou, Prof. MD
qian.zhou@usb.ch
+41 3286828
Time Frame
Start Date: 2025-07-17
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 140
Treatments
Experimental: telemedicine guided care group
Patients will be instructed to response to questions using the App daily. The parameters and questionnaires will be evaluated by the Telemedicine team, and participants will be contacted via phone 1 week after discharge and subsequently every 7-10 days to discuss the up-titration of the HF medications.
Active_comparator: usual care group
usual care according to local practice
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Basel, Switzerland

This content was sourced from clinicaltrials.gov