Invasive Hemodynamic Study of Structural Heart Diseases: A Monocentric, Non-Randomized Approach
The VHD PV loop study intends to assess invasive right ventricular to pulmonary artery (RV-PA) coupling in patients with valvular heart disease (VHD). Invasive RV-PA coupling is measured by using conductance catheters, the gold standard assessment for ventricular physiology. Several non-invasive parameters have been reported as surrogates for this complex physiological entity, but none of them has been tested against the gold-standard in this population. Based on this, our main objective is to assess the correlation of imaging derived RV-PA coupling in comparison to the invasive measurement.
• Adult patients (≥ 18 years old);
• Patients with severe structural heart disease (meeting at least one of the following three criteria):
‣ Heart failure with moderate-to-severe or severe secondary mitral regurgitation
⁃ At least severe tricuspid regurgitation
⁃ Significant pulmonary valve stenosis and/or regurgitation