Heart Failure Clinical Trials

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Prospective, Randomized Open Label Trial of Telemedically Assisted Optimization for Heart Failure Patients Before Cardiac Surgery to Improve Perioperative Outcome

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Patients with heart failure undergoing cardiac surgery face a significantly increased perioperative risk, yet no standardized strategy exists to mitigate this risk effectively. Current preoperative management relies on optimization of medical therapy without a structured prehabilitation approach. Given the strong association between eleveated preoperative N-terminal pro-B-type natriuretic peptide levels and postoperative outcomes, patients at increased risk could be identified using this biomarker. Telemedical disease management programs have demonstrated efficacy in outpatient heart failure care, but their role in preoperative optimization remains underexplored. This study aims to assess whether a structured, multidisciplinary, telemedicine-assisted prehabilitation program can reduce perioperative complications, and improve surgical outcomes.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Indication for elective cardiac surgery in the Heart team

• NTproBNP ≥ 1500 ng/L

• ≥ 18 years willing to participate in trial

• Written informed consent

Locations
Other Locations
Austria
Medical University of Innsbruck - Department of Cardiology & Department of Cardiac Surgery
RECRUITING
Innsbruck
Contact Information
Primary
Can Gollmann-Tepeköylü, Prof.
can.gt@i-med.ac.at
+4351250480466
Backup
Leo Winter-Pölzl, MD
leo.poelzl@i-med.ac.at
+4351250484591
Time Frame
Start Date: 2026-02-16
Estimated Completion Date: 2034-01-01
Participants
Target number of participants: 162
Treatments
No_intervention: Control arm - Standard of care treatment
Receives standard preoperative care until surgery.
Experimental: PREPARE-HF
Preoperative Heart Failure Optimization and Telemedicine Integration
Related Therapeutic Areas
Sponsors
Leads: Medical University Innsbruck

This content was sourced from clinicaltrials.gov