Kenji Sugai practices in Tokyo, Japan. Sugai is rated as an Elite expert by MediFind in the treatment of Hemimegalencephaly. He is also highly rated in 18 other conditions, according to our data. His top areas of expertise are Hemimegalencephaly, Epilepsy in Children, Epilepsy, and Seizures.
William Dobyns is a Neurologist and a Pediatrics expert in Chicago, Illinois. Dobyns has been practicing medicine for over 45 years and is rated as an Elite expert by MediFind in the treatment of Hemimegalencephaly. He is also highly rated in 48 other conditions, according to our data. His top areas of expertise are Polymicrogyria, Lissencephaly, Increased Head Circumference, and Cortical Dysplasia. Dobyns is currently accepting new patients.
Masayuki Sasaki practices in Tokyo, Japan. Sasaki is rated as an Elite expert by MediFind in the treatment of Hemimegalencephaly. He is also highly rated in 46 other conditions, according to our data. His top areas of expertise are Hemimegalencephaly, Epilepsy in Children, Cortical Dysplasia, and Epilepsy.
Summary: Brain somatic mutations in genes belonging to the mTOR signaling pathway are a frequent cause of cortical malformations, including focal cortical dysplasia or hemimegalencephaly. The present study aims to search for brain somatic mutations in paired blood-brain samples and perform functional validation in children with drug-resistant focal epilepsy
Summary: Refractory epilepsy, meaning epilepsy that no longer responds to medication, is a common neurosurgical indication in children. In such cases, surgery is the treatment of choice. Complete resection of affected brain tissue is associated with highest probability of seizure freedom. However, epileptogenic brain tissue is visually identical to normal brain tissue, complicating complete resection. Mode...
Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center