Hemimegalencephaly
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Learn About Hemimegalencephaly

What is the definition of Hemimegalencephaly?
Hemimegalencephaly is a rare malformation involving one side of the brain. It may occur alone or in association with other syndromes such as Proteus syndrome, tuberous sclerosis, linear sebaceous nevus syndrome, neurofibromatosis, Sturge-Weber syndrome, or Klippel-Trenaunay syndrome. Children with this disorder may have a large, asymmetrical head accompanied by seizures, partial paralysis, and impaired cognitive development. The cause of Hemimegalencephaly is not fully understood, but involves a disturbance of cells early in development and likely involves genes involved in patterning and symmetry.
What are the alternative names for Hemimegalencephaly?
  • Hemimegalencephaly
  • Macrencephaly
  • Unilateral Megalencephaly
Who are the top Hemimegalencephaly Local Doctors?
Elite in Hemimegalencephaly
Elite in Hemimegalencephaly
Referral may be required

Children's National Hospital

111 Michigan Ave NW, 
Washington, DC 
Languages Spoken:
English
Offers Telehealth

Tammy Tsuchida is a Neurologist practicing medicine in Washington, Washington, D.c.. Dr. Tsuchida is rated as an Elite provider by MediFind in the treatment of Hemimegalencephaly. She is also highly rated in 11 other conditions, according to our data. Her clinical expertise encompasses Epilepsy in Children, Hemimegalencephaly, Seizures, Epilepsy, and Liver Embolization.

Elite in Hemimegalencephaly
Neurosurgery
Elite in Hemimegalencephaly
Neurosurgery
Referral may be required

Office

5767 W Century Blvd Ste 200, 
Los Angeles, CA 
Languages Spoken:
English

Gary Mathern is a Neurosurgery provider practicing medicine in Los Angeles, California. Dr. Mathern is rated as an Elite provider by MediFind in the treatment of Hemimegalencephaly. He is also highly rated in 9 other conditions, according to our data. His clinical expertise encompasses Hemimegalencephaly, Cortical Dysplasia, Increased Head Circumference, and Epilepsy.

 
 
 
 
Learn about our expert tiers
Learn More
Elite in Hemimegalencephaly
Medical Genetics | Pediatrics | Pediatric Neurology
Elite in Hemimegalencephaly
Medical Genetics | Pediatrics | Pediatric Neurology
Referral may be required

Fairview Express Care

717 Delaware St Se, Suite 340, 
Minneapolis, MN 
Experience:
48+ years
Languages Spoken:
English
Accepting New Patients

William Dobyns is a Medical Genetics specialist and a Pediatrics provider practicing medicine in Minneapolis, Minnesota. He has been practicing medicine for over 48 years. Dr. Dobyns is rated as an Elite provider by MediFind in the treatment of Hemimegalencephaly. He is also highly rated in 46 other conditions, according to our data. His clinical expertise encompasses Increased Head Circumference, Lissencephaly, Cerebellar Hypoplasia, and Cortical Dysplasia. Dr. Dobyns is currently accepting new patients.

What are the latest Hemimegalencephaly Clinical Trials?
Genetic and Electrophysiologic Study in Focal Drug-resistant Epilepsies

Summary: Brain somatic mutations are increasingly recognized as a major cause of focal epilepsies. These include mTOR pathway mutations underlying cortical malformations such as focal cortical dysplasia and hemimegalencephaly, and SLC35A2 mutations in MOGHE, and activating variants in the SHH pathway in hypothalamic hamartomas. This study aims to identify brain somatic mutations using paired blood-brain sa...

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Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center