Hemoglobin C DiseaseSymptoms, Doctors, Treatments, Advances & More
Learn About Hemoglobin C Disease
Hemoglobin C disease is a blood disorder passed down through families. It leads to a type of anemia, which occurs when red blood cells break down earlier than normal.
Clinical hemoglobin C
Hemoglobin C is an abnormal type of hemoglobin, the protein in red blood cells that carries oxygen. It is a type of hemoglobinopathy. The disease is caused by a problem with a gene called beta globin.
The disease most often occurs in African Americans. You are more likely to have hemoglobin C disease if someone in your family has had it.
Most people do not have symptoms. In some cases, jaundice may occur. Some people may develop gallstones that need to be treated.
In most cases, no treatment is needed. Folic acid supplements may help your body produce normal red blood cells and improve the symptoms of the anemia.
Ogobara Doumbo practices practicing medicine in Bamako, Mali. Doumbo is rated as an Elite expert by MediFind in the treatment of Hemoglobin C Disease. They are also highly rated in 8 other conditions, according to our data. Their clinical expertise encompasses Malaria, Hemoglobin C Disease, Primary Amebic Meningoencephalitis, and Sepsis.
Northwest Oncology And Hematology SC
Wajihuddin Syed is an Oncologist and a Hematologist practicing medicine in Hoffman Estates, Illinois. Dr. Syed is rated as an Experienced provider by MediFind in the treatment of Hemoglobin C Disease. He is also highly rated in 11 other conditions, according to our data. His clinical expertise encompasses Breast Cancer, Chromophobe Renal Cell Carcinoma, Wilms Tumor, and Clear Cell Sarcoma. Dr. Syed is board certified in American Board Of Internal Medicine, Hematology, The American Board Of Internal Medicine - Hematology, The American Board Of Internal Medicine - Medical Oncology, The American Board Of Internal Medicine - Internal Medicine, and Medical Oncology & Hematology, Internal Medicine, American Board Of Internal Medicine. Dr. Syed is currently accepting new patients.
Duke Adult Comprehensive Sickle Cell Center - Clinic 2N
John Strouse is a Hematologist and a Pediatrics provider practicing medicine in Durham, North Carolina. Dr. Strouse is rated as an Advanced provider by MediFind in the treatment of Hemoglobin C Disease. He is also highly rated in 11 other conditions, according to our data. His clinical expertise encompasses Sickle Cell Disease, Hemoglobinopathy, Congenital Hemolytic Anemia, Thrombectomy, and Bone Marrow Aspiration. Dr. Strouse is board certified in American Board Of Internal Med, Hematology , American Board Of Pediatrics, Pediatric Hematology-Oncology, and American Board Of Pediatrics, General Pediatrics . Dr. Strouse is currently accepting new patients.
People with hemoglobin C disease can expect to lead a normal life.
Complications may include:
- Anemia
- Gallbladder disease
- Enlargement of the spleen
Contact your health care provider if you have symptoms of hemoglobin C disease.
You may want to seek genetic counseling if you are at high risk for the condition and are considering having a baby.
Published Date: January 29, 2026
Published By: Warren Brenner, MD, Oncologist, Lynn Cancer Institute, Boca Raton, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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Smith-Whitley K, Kwiatkowski JL. Hemoglobinopathies. In: Kliegman RM, St. Geme JW, Blum NJ, et al, eds. Nelson Textbook of Pediatrics. 22nd ed. Philadelphia, PA: Elsevier; 2025:chap 511.
So JCC, Ma ESK. Hemoglobin and hemoglobinopathies. In: Rifai N, Chiu RWK, Young I, Burnham CAD, Wittwer CT, eds. Tietz Textbook of Laboratory Medicine. 7th ed. St Louis, MO: Elsevier; 2023:chap 77.
Steinberg MH, Benz EJ, Ebert BL. Pathobiology of the human erythrocyte and its hemoglobins. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 34.