Hemoglobin C Disease Overview
Learn About Hemoglobin C Disease
Hemoglobin C disease is a blood disorder passed down through families. It leads to a type of anemia, which occurs when red blood cells break down earlier than normal.
Clinical hemoglobin C
Hemoglobin C is an abnormal type of hemoglobin, the protein in red blood cells that carries oxygen. It is a type of hemoglobinopathy. The disease is caused by a problem with a gene called beta globin.
The disease most often occurs in African Americans. You are more likely to have hemoglobin C disease if someone in your family has had it.
Most people do not have symptoms. In some cases, jaundice may occur. Some people may develop gallstones that need to be treated.
In most cases, no treatment is needed. Folic acid supplements may help your body produce normal red blood cells and improve the symptoms of the anemia.
Ogobara Doumbo practices in Bamako, Mali. Doumbo is rated as an Elite expert by MediFind in the treatment of Hemoglobin C Disease. Their top areas of expertise are Malaria, Hemoglobin C Disease, Primary Amebic Meningoencephalitis, and Sepsis.
Prisma Health University Medical Group
Jay Walls is a Hematologist Oncology specialist and an Oncologist in Greenville, South Carolina. Dr. Walls is rated as an Advanced provider by MediFind in the treatment of Hemoglobin C Disease. His top areas of expertise are Essential Thrombocythemia, Childhood Iron Deficiency Anemia, Sickle Cell Disease, Hemoglobin SC Disease, and Bone Marrow Aspiration. Dr. Walls is currently accepting new patients.
Musc Community Physicians
Daniel Landau is a Hematologist Oncology specialist and a Hematologist in Orangeburg, South Carolina. Dr. Landau is rated as an Advanced provider by MediFind in the treatment of Hemoglobin C Disease. His top areas of expertise are WT1-Related Wilms Tumor Syndromes, Clear Cell Sarcoma, Familial Prostate Cancer, Multiple Myeloma, and Bone Marrow Aspiration. Dr. Landau is currently accepting new patients.
People with hemoglobin C disease can expect to lead a normal life.
Complications may include:
- Anemia
- Gallbladder disease
- Enlargement of the spleen
Contact your health care provider if you have symptoms of hemoglobin C disease.
You may want to seek genetic counseling if you are at high risk for the condition and are considering having a baby.
Summary: The primary objective of this study is to evaluate a potential behavioral intervention (MED-Go app). To meet this objective, the researchers will conduct a pilot randomized controlled trial to test the feasibility and acceptability of MED-Go app in adolescents and young adults (AYA) with sickle cell disease (SCD). The long-term goal of this research is to promote medication adherence behavior and ...
Published Date: March 31, 2024
Published By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Howard J. Sickle cell disease and other hemoglobinopathies. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 149.
Smith-Whitley K, Kwiatkowski JL. Hemoglobinopathies. In: Kliegman RM, St. Geme JW, Blum NJ, et al, eds. Nelson Textbook of Pediatrics. 22nd ed. Philadelphia, PA: Elsevier; 2025:chap 511.
So JCC, Ma ESK. Hemoglobin and hemoglobinopathies. In: Rifai N, Chiu RWK, Young I, Burnham CAD, Wittwer CT, eds. Tietz Textbook of Laboratory Medicine. 7th ed. St Louis, MO: Elsevier; 2023:chap 77.
Wilson CS, Vergara-Lluri ME, Brynes RK. Evaluation of anemia, leukopenia, and thrombocytopenia. In: Jaffe ES, Arber DA, Campo E, Harris NL, Quintanilla-Martinez L, eds. Hematopathology. 2nd ed. Philadelphia, PA: Elsevier; 2017:chap 11.