Learn About Hemolytic Anemia

What is the definition of Hemolytic Anemia?

Anemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues.

Normally, red blood cells last for about 120 days in the body. In hemolytic anemia, red blood cells in the blood are destroyed earlier than normal.

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What are the alternative names for Hemolytic Anemia?

Anemia - hemolytic

What are the causes of Hemolytic Anemia?

The bone marrow is mostly responsible for making new red cells. Bone marrow is the soft tissue in the center of bones that helps form all blood cells.

Hemolytic anemia occurs when the bone marrow isn't making enough red cells to replace the ones that are being destroyed.

There are several possible causes of hemolytic anemia. Red blood cells may be destroyed due to:

  • An autoimmune problem in which the immune system mistakenly sees your own red blood cells as foreign substances and destroys them
  • Genetic defects within the red cells (such as sickle cell anemia, thalassemia, and G6PD deficiency)
  • Exposure to certain chemicals, medicines, and toxins
  • Infections
  • Blood clots in small blood vessels
  • Transfusion of blood from a donor with a blood type that does not match yours
What are the symptoms of Hemolytic Anemia?

You may not have symptoms if the anemia is mild. If the problem develops slowly, the first symptoms may be:

  • Feeling weak or tired more often than usual, or with exercise
  • Feelings that your heart is pounding or racing
  • Headaches
  • Problems concentrating or thinking

If the anemia gets worse, symptoms may include:

  • Lightheadedness when you stand up
  • Pale skin
  • Shortness of breath
  • Sore tongue
  • Enlarged spleen
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What are the current treatments for Hemolytic Anemia?

Treatment depends on the type and cause of the hemolytic anemia:

  • In emergencies, a blood transfusion may be needed.
  • For immune causes, medicines that suppress the immune system may be used.
  • When blood cells are being destroyed at a fast pace, the body may need extra folic acid and iron supplements to replace what is being lost.

In rare cases, surgery is needed to take out the spleen. This is because the spleen acts as a filter that removes abnormal cells from the blood.

Who are the top Hemolytic Anemia Local Doctors?
Elite
Highly rated in
7
conditions
Hematology Oncology
Pediatrics

Duke Health

Private Diagnostic Clinic

40 Duke Medicine Cir 
Durham, NC 27710

Nirmish Shah is a Hematologist Oncology specialist and a Pediatrics doctor in Durham, North Carolina. Dr. Shah has been practicing medicine for over 22 years and is rated as an Elite doctor by MediFind in the treatment of Hemolytic Anemia. He is also highly rated in 7 other conditions, according to our data. His top areas of expertise are Sickle Cell Disease, Congenital Hemolytic Anemia, Hemoglobinopathy, and Hemolytic Anemia. He is licensed to treat patients in North Carolina. Dr. Shah is currently accepting new patients.

Elite
Highly rated in
14
conditions
Hematology
Pediatric Hematology Oncology

Duke Health

Duke University Hospital

2301 Erwin Rd 
Durham, NC 27705

John Strouse is a Hematologist and a Pediatric Hematologist Oncology doctor in Durham, North Carolina. Dr. Strouse has been practicing medicine for over 26 years and is rated as an Elite doctor by MediFind in the treatment of Hemolytic Anemia. He is also highly rated in 14 other conditions, according to our data. His top areas of expertise are Sickle Cell Disease, Hemoglobinopathy, Congenital Hemolytic Anemia, and Hemolytic Anemia. He is licensed to treat patients in Maryland. Dr. Strouse is currently accepting new patients.

 
 
 
 
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Elite
Highly rated in
14
conditions
Pediatric Hematology Oncology
Pediatrics

Cincinnati Childrens Hospital Medical Center

Burnet Campus

3333 Burnet Ave 
Cincinnati, OH 45229

Russell Ware is a Pediatric Hematologist Oncology specialist and a Pediatrics doctor in Cincinnati, Ohio. Dr. Ware has been practicing medicine for over 31 years and is rated as an Elite doctor by MediFind in the treatment of Hemolytic Anemia. He is also highly rated in 14 other conditions, according to our data. His top areas of expertise are Sickle Cell Disease, Hemoglobinopathy, Congenital Hemolytic Anemia, and Hemolytic Anemia. He is licensed to treat patients in Ohio. Dr. Ware is currently accepting new patients.

What is the outlook (prognosis) for Hemolytic Anemia?

Outcome depends on the type and cause of hemolytic anemia. Severe anemia can make heart disease, lung disease, or cerebrovascular disease worse.

When should I contact a medical professional for Hemolytic Anemia?

Call your health care provider if you develop symptoms of hemolytic anemia.

Red blood cells, sickle cell
Red blood cells - multiple sickle cells
Red blood cells - sickle cells
Red blood cells - sickle and Pappenheimer
Blood cells
What are the latest Hemolytic Anemia Clinical Trials?
Real Life Use of Ravulizumab in Italian Patients With Paroxysmal Nocturnal Hemoglobinuria a Multicenter Observational Retrospective and Prospective Cohort Study.
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Effect of MitoQ on Platelet Function and Reactive Oxygen Species (ROS) Generation in Patients With Sickle Cell Anemia
What are the Latest Advances for Hemolytic Anemia?
Hemolytic paroxysmal nocturnal hemoglobinuria: 20 years of medical progress.
Cold agglutinin disease secondary to severe SARS-CoV-2 treated with eculizumab.
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Mitapivat versus Placebo for Pyruvate Kinase Deficiency.
Who are the sources who wrote this article ?

Published Date : February 06, 2020
Published By : Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Brodsky RA. Paroxysmal nocturnal hemoglobinuria. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier; 2018:chap 31.

Gallagher PG. Hemolytic anemias: red blood cell membrane and metabolic defects. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 152.

Kumar V, Abbas AK, Aster JC. Hematopoietic and lymphoid systems. In: Kumar V, Abbas AK, Aster JC, eds. Robbins Basic Pathology. 10th ed. Philadelphia, PA: Elsevier; 2018:chap 12.