Learn About Hemolytic Crisis

What is the definition of Hemolytic Crisis?

Hemolytic crisis occurs when large numbers of red blood cells are destroyed over a short time. The loss of red blood cells occurs much faster than the body can produce new red blood cells.

Save information for later
Sign Up
What are the alternative names for Hemolytic Crisis?

Hemolysis - acute

What is some background information about Hemolytic Crisis?

During a hemolytic crisis, the body cannot make enough red blood cells to replace those that are destroyed. This causes acute and often severe anemia.

The part of red blood cells that carries oxygen (hemoglobin) is released into the bloodstream. This can lead to kidney damage.

What are the causes of Hemolytic Crisis?

Causes of hemolysis include:

  • A lack of certain proteins inside red blood cells
  • Autoimmune diseases
  • Certain infections
  • Defects in the hemoglobin molecules inside red blood cells
  • Defects of the proteins that make up the internal framework of red blood cells
  • Side effects of certain medicines
  • Reactions to blood transfusions
When should I contact a medical professional for Hemolytic Crisis?

Call your health care provider if you have:

  • Symptoms of anemia, including pale skin or fatigue, especially if these symptoms get worse
  • Urine that is red, red-brown, or brown (tea-colored)
What should I expect during a doctor appointment?

Emergency treatment may be necessary. This may include a hospital stay, oxygen, blood transfusions, and other treatments.

When your condition is stable, your provider will perform a physical examination and ask about your medical history and symptoms. The physical exam may show swelling of the spleen (splenomegaly).

Tests that may be done include:

  • Blood chemistry panel
  • Complete blood count (CBC)
  • Coombs test
  • Haptoglobin
  • Lactate dehydrogenase

Treatment depends on the cause of hemolysis.

Who are the top Hemolytic Crisis Local Doctors?
Highly rated in

Dmitry Rogachev National Medical Research Center Of Pediatric Hematology

Moscow, MOW, RU 

Elena Seregina is in Moscow, Russian Federation. Seregina is rated as an Elite expert by MediFind in the treatment of Hemolytic Crisis. She is also highly rated in 1 other condition, according to our data. Her top areas of expertise are Hemolytic Crisis, Hemolytic Anemia, Hereditary Spherocytosis, and Anemia.

Highly rated in
Hematology Oncology

WellStar Health System

Northwest Georgia Oncology Centers WellStar

6002 Professional Pkwy 
Douglasville, GA 30134

Navin Wadehra is a Hematologist Oncology specialist and an Oncologist in Douglasville, Georgia. Dr. Wadehra has been practicing medicine for over 23 years and is rated as a Distinguished doctor by MediFind in the treatment of Hemolytic Crisis. He is also highly rated in 28 other conditions, according to our data. His top areas of expertise are Paget Disease of the Breast, Hereditary Spherocytosis, Hemolytic Crisis, and Congenital Hemolytic Anemia. He is board certified in Hematology/oncology, Hematology, and Medical Oncology and licensed to treat patients in Georgia. Dr. Wadehra is currently accepting new patients.

Learn about our expert tiers
Learn more
Highly rated in

Serbian Academy Of Sciences And Arts

Belgrade, SE, RS 

Bela Balint is in Belgrade, Serbia. Balint is rated as a Distinguished expert by MediFind in the treatment of Hemolytic Crisis. They are also highly rated in 1 other condition, according to our data. Their top areas of expertise are Hemolytic Crisis, Anemia, Diffuse Large B-Cell Lymphoma, and Somatostatinoma.

What are the latest Hemolytic Crisis Clinical Trials?
Match to trials
Find the right clinical trials for you in under a minute
Get started
What are the Latest Advances for Hemolytic Crisis?
Genotypes and phenotypes of G6PD deficiency among Indonesian females across diagnostic thresholds of G6PD activity guiding safe primaquine therapy of latent malaria.
A Case of COVID-19 in a Patient with Asymptomatic Hemoglobin D Thalassemia and Glucose-6-Phosphate Dehydrogenase Deficiency.
Tired of the same old research?
Check Latest Advances
Who are the sources who wrote this article ?

Published Date : February 06, 2020
Published By : Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Gallagher PG. Hemolytic anemias: red blood cell membrane and metabolic defects. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 152.