Condition 101 About Hemophilia B

What is the definition of Hemophilia B?

Hemophilia B is a bleeding disorder that slows the blood clotting process. People with this disorder experience prolonged bleeding or oozing following an injury or surgery. In severe cases of hemophilia, heavy bleeding occurs after minor injury or even in the absence of injury. Serious complications can result from bleeding into the joints, muscles, brain, or other internal organs. Milder forms may not become apparent until abnormal bleeding occurs following surgery or a serious injury. People with an unusual form of hemophilia B, known as hemophilia B Leyden, experience episodes of excessive bleeding in childhood but have few bleeding problems after puberty. Hemophilia B is inherited in an X-linked recessive pattern and is caused by mutations in the F9 gene.

What are the alternative names for Hemophilia B?

  • Christmas disease
  • Factor IX deficiency
  • HEM B

Latest Advances On Hemophilia B

  • Condition: Moderate/Severe Hemophilia B
  • Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
  • Treatment Used: Nonacog Gamma, a Recombinant Factor IX
  • Number of Patients: 0
  • Published —
This study evaluated the hemostatic (blood loss prevention) safety of a recombinant factor IX concentrate, nonacog gamma (BAX 326, Rixubis® ), in previously treated patients (PTPs) with severe or moderately severe hemophilia B undergoing elective surgery.

Clinical Trials For Hemophilia B

Clinical Trial
  • Status: Not yet recruiting
  • Phase: Phase 4
  • Intervention Type: Drug
  • Participants: 55
  • Start Date: March 31, 2021
Safety of SEVENFACT® for the Treatment of Bleeding Events in Patients With Hemophilia A or B With Inhibitors