Efficacy and Safety of Fecal Microbiota Transplantation for Ulcerative Colitis
Who is this study for? Patients with ulcerative colitis
Status: Recruiting
Location: See location...
Intervention Type: Drug, Procedure
Study Type: Interventional
Study Phase: Phase 2/Phase 3
SUMMARY
Fecal microbiota transplantation (FMT) is a strategy that infuses a fecal suspension containing a healthy donor's microbiota into a patient's gut to restore his/her intestinal microbiome. Fecal microbiota transplantation has been used for several disease，but the efficacy of ulcerative colitis(UC) by fecal microbiota transplantation needs to be further explored.The investigators propose to determine the efficiency and safety of FMT in patients with ulcerative colitis(UC).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:
• Active, moderate to severe severity (Mayo score more than 6)
• Safety using history of 5-ASA
• Able to undergo endoscopy examination
Locations
Other Locations
China
Guangzhou First People's Hospital
RECRUITING
Guangzhou
Contact Information
Primary
Hongli Huang, MM
honglisums@126.com
86-13631316718
Backup
Huiting Chen, MM
gracy1977@tom.com
86-13926055294
Time Frame
Start Date: 2019-01-20
Estimated Completion Date: 2030-12-31
Participants
Target number of participants: 120
Treatments
Experimental: Fecal microbiota transplantation
Fecal microbiota transplantation
Sham_comparator: placebo fecal microbiota transplantation
Infusion of Saline
Other: Traditional treatments
Drug:5-Aminosalicylic acid(5-ASA) and/or Prednisone
Related Therapeutic Areas
Sponsors
Leads: Guangzhou First People's Hospital