Histologic Healing in IBD: Comparison of Standard Scores With Expression of Claudin 2 and Impact on Outcomes
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
In view of the increasing evidence of the importance of mucosal healing as a combination of endoscopic and histologic healing, and the complexity and lack of complete agreement of the evaluation of histologic healing in IBD, the aim of this study will be to evaluate the accuracy of a new methodology, the immunostaining for Claudine 2 as compared to others standard well-accepted scoring for histologic activity in IBD. The aim is compare the accuracy of this methodology and in addition the correlation with outcomes (i.e. relapse, hospitalization, surgery).
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Confirmed diagnosis of IBD
Locations
Other Locations
Italy
Gastroenterology IRCCS San Donato Policlinic
RECRUITING
San Donato Milanese
Contact Information
Primary
Vito Annese, Prof. PI
vitoannese1@gmail.com
0039 3388261812
Backup
Antonella Bianchi, Study coordinator
antonella.bianchi2@gruopposandonato.it
0039 025277
Time Frame
Start Date: 2025-02-14
Estimated Completion Date: 2027-09
Participants
Target number of participants: 100
Treatments
IBD patients
Patients with ulcerative colitis and Crohn' disease
Related Therapeutic Areas
Sponsors
Leads: IRCCS Policlinico S. Donato
Collaborators: Asst Degli Spedali Civili Di Brescia