What is the definition of Hepatic Hemangioma?

A hepatic hemangioma is a liver mass made of widened (dilated) blood vessels. It is not cancerous.

What are the alternative names for Hepatic Hemangioma?

Liver hemangioma; Hemangioma of the liver; Cavernous hepatic hemangioma; Infantile hemangioendothelioma; Multinodular hepatic hemangiomatosis

What are the causes for Hepatic Hemangioma?

A hepatic hemangioma is the most common type of liver mass that is not caused by cancer. It may be a birth defect.

Hepatic hemangiomas can occur at any time. They are most common in people in their 30s to 50s. Women get these masses more often than men. The masses are often bigger in size.

Babies may develop a type of hepatic hemangioma called benign infantile hemangioendothelioma. This is also known as multinodular hepatic hemangiomatosis. This is a rare, noncancerous tumor that has been linked to high rates of heart failure and death in infants. Infants are most often diagnosed by the time they are 6 months old.

What are the symptoms for Hepatic Hemangioma?

Some hemangiomas may cause bleeding or interfere with organ function. Most do not produce symptoms. In rare cases, the hemangioma may rupture.

What are the current treatments for Hepatic Hemangioma?

Most of these tumors are treated only if there is ongoing pain.

Treatment for infantile hemangioendothelioma depends on the child's growth and development. The following treatments may be needed:

  • Inserting a material in a blood vessel of the liver to block it (embolization)
  • Tying off (ligation) a liver artery
  • Medicines for heart failure
  • Surgery to remove the tumor

What is the outlook (prognosis) for Hepatic Hemangioma?

Surgery can cure a tumor in an infant if it is only in one lobe of the liver. This can be done even if the child has heart failure.

What are the possible complications for Hepatic Hemangioma?

Pregnancy and estrogen-based medicines can cause these tumors to grow.

The tumor may rupture in rare cases.



Di Bisceglie AM, Befeler AS. Hepatic tumors and cysts. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 96.

Mendes BC, Tollefson MM, Bower TC. Pediatric vascular tumors. In: Sidawy AN, Perler BA, eds. Rutherford's Vascular Surgery and Endovascular Therapy. 9th ed. Philadelphia, PA: Elsevier; 2019:chap 188.

Soares KC, Pawlik TM. The management of liver hemangioma. In: Cameron JL, Cameron AM, eds. Current Surgical Therapy. 12th ed. Philadelphia, PA: Elsevier; 2017:349-354.

  • Condition: Hepatic Hemangioma
  • Journal: Medicine
  • Treatment Used: Laparoscopic versus Open Surgery
  • Number of Patients: NULL
  • Published —
The study researched the outcomes of laparoscopic versus open surgery for treating hepatic hemangioma.
  • Condition: Large Hepatic Hemangiomas
  • Journal: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
  • Treatment Used: Microwave Ablation (MWA) vs. Transcatheter Arterial Embolization (TAE)
  • Number of Patients: 135
  • Published —
This study evaluated the safety and effect of microwave ablation (MWA) versus transcatheter arterial embolization (TAE) for the treatment of large hepatic hemangiomas.
Clinical Trial
  • Status: Not yet recruiting
  • Phase: Phase 4
  • Intervention Type: Drug
  • Participants: 36
  • Start Date: July 2020
Sirolimus in the Treatment for Propranolol-resistant Infantile Hepatic Hemangioendothelioma