Hepatic Venoocclusive Disease with Immunodeficiency Overview

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Learn About Hepatic Venoocclusive Disease with Immunodeficiency

What is the definition of Hepatic Venoocclusive Disease with Immunodeficiency?
Hepatic veno-occlusive disease with immunodeficiency (VODI) is a genetic disorder of the liver and immune system that appears before the age of 12 months in which the small veins of the liver become blocked.
What are the symptoms of Hepatic Venoocclusive Disease with Immunodeficiency?
Symptoms of veno-occlusive disease with immunodeficiency may include failure to thrive, abnormally small head, liver enlargement, fibrosis of the liver, recurrent bacterial and opportunistic infections, diarrhea, anemia, fluid in the abdomen (ascites), seizures, weakness on one side of the body (hemiparesis), leg paralysis (paraplegia), lung fibrosis, lung hemorrhage, recurrent pneumonia, recurrent ear infections, yellowing of the skin, mucous membranes, and whites of eyes (jaundice), low platelets, urinary retention, portal hypertension (high blood pressure), liver abnormalities, fibrosis of the heart, and liver failure. Most individuals with veno-occlusive disease with immunodeficiency do not survive childhood, while a few may survive into early adulthood.
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What are the current treatments for Hepatic Venoocclusive Disease with Immunodeficiency?
Treatment for veno-occlusive disease with immunodeficiency include intravenous immunoglobulin (IVIG), pneumocystis jeroveci (fungal infection) prophylaxis, treatment for infections, and liver transplantation in selected patients.
Who are the top Hepatic Venoocclusive Disease with Immunodeficiency Local Doctors?
Hematology | Oncology | Hematology Oncology
Hematology | Oncology | Hematology Oncology

MD Anderson

2130 W Holcombe Blvd, Life Sciences Plaza, 
Houston, TX 
 (25.9 mi)
Languages Spoken:
English
Offers Telehealth

Tapan Kadia is a Hematologist and an Oncologist in Houston, Texas. Dr. Kadia and is rated as an Advanced provider by MediFind in the treatment of Hepatic Venoocclusive Disease with Immunodeficiency. His top areas of expertise are Acute Myeloid Leukemia (AML), Leukemia, Myelodysplastic Syndrome (MDS), Bone Marrow Aspiration, and Bone Marrow Transplant.

Hagop M. Kantarjian
Oncology | Hematology
Oncology | Hematology

MD Anderson

1515 Holcombe Blvd, 
Houston, TX 
 (25.3 mi)
Languages Spoken:
English

Hagop Kantarjian is an Oncologist and a Hematologist in Houston, Texas. Dr. Kantarjian and is rated as a Distinguished provider by MediFind in the treatment of Hepatic Venoocclusive Disease with Immunodeficiency. His top areas of expertise are Chronic Myelogenous Leukemia (CML), Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Bone Marrow Transplant, and Bone Marrow Aspiration.

 
 
 
 
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Elias J. Jabbour
Hematology Oncology | Hematology | Oncology
Hematology Oncology | Hematology | Oncology

MD Anderson

2130 W Holcombe Blvd, Life Sciences Plaza, 
Houston, TX 
 (25.9 mi)
Languages Spoken:
English

Elias Jabbour is a Hematologist Oncology specialist and a Hematologist in Houston, Texas. Dr. Jabbour and is rated as a Distinguished provider by MediFind in the treatment of Hepatic Venoocclusive Disease with Immunodeficiency. His top areas of expertise are Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML), Leukemia, Bone Marrow Aspiration, and Bone Marrow Transplant.

What are the latest Hepatic Venoocclusive Disease with Immunodeficiency Clinical Trials?
Cell Free DNA Profiling As a Tool to Monitor Clinically-Relevant Events in Allogeneic Hematopoietic Stem Cell Transplantation

Summary: Allogeneic hematopoietic stem cell transplantation (HSCT) is a life-saving treatment for people with severe blood-related diseases. However, it comes with serious risks, including a condition called graft-versus-host disease (GVHD), where the transplanted cells attack the patient's body. GVHD can occur in about 50% of patients acutely and 35% in a chronic form, potentially affecting organs like th...

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Evaluation, in Humans, of the Correlation Between Hepatotoxicity, Neurotoxicity Induced by Oxaliplatin, and Blood Levels of HMGB1

Summary: Oesogastric and pancreatic adenocarcinomas are poor-prognosis cancers. Incidence of pancreatic cancer drastically increases to such an extent that it will become the second cause of cancer's mortality by 2030. A major challenge is to optimize the therapies for localized setting, when oxaliplatin-based chemotherapy is the standard, before and after surgical excision. Because in 50% of cases oxalipl...

What are the Latest Advances for Hepatic Venoocclusive Disease with Immunodeficiency?