Retrospective and Prospective Multi-center Clinical Study of Magnetic Resonance Elastography in Evaluating Hepatic Fibrosis in Chronic Viral Hepatitis B
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Observational
SUMMARY
How to construct a non-invasive, accurate, and convenient method to evaluate the severity of liver fibrosis (LF) is an important general problem in the management of patients with chronic hepatitis B (CHB). We plan to investigate the ability of magnetic resonance elastography (MRE) to grade fibrosis in chronic hepatitis B and apply to clinical longitudinal follow-up.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Age ≥ 18 years old
• Confirmed CHB (laboratory, imaging and clinical tests)
• MRE within 6 months before and after liver biopsy
• Treatment-naïve
• Child-Pugh Grade A (\<7 points)
• Written informed consent in prospective follow-up cohort
Locations
Other Locations
China
Shengjing Hospital
RECRUITING
Shenyang
Contact Information
Primary
Yiyang Wang
15291014907@163.com
+86 15291014907
Backup
Yu Shi
18940259980@163.com
+86 189 4025 9980
Time Frame
Start Date: 2025-01-01
Estimated Completion Date: 2026-07-01
Participants
Target number of participants: 600
Treatments
Retrospective cohort of patients confirmed diagnosed with chronic hepatitis B
Patients aged ≥ 18 who have been diagnosed with chronic hepatitis B from Jan 2010 to Oct 2024
Prospective follow-up cohort of patients confirmed diagnosed with chronic hepatitis B
Patients aged ≥ 18 who have been diagnosed with chronic hepatitis B, both treated and untreated from Aug 2022
Related Therapeutic Areas
Sponsors
Leads: Shengjing Hospital