Hepatitis D Overview

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Learn About Hepatitis D

View Main Condition: Hepatitis

What is the definition of Hepatitis D?
Hepatitis D, also known as “Delta Hepatitis,” is an infection of the liver caused by the hepatitis D virus (HDV) that causes liver inflammation and damage. Hepatitis D can only occur in individuals who are already infected with the hepatitis B virus (HBV). Hepatitis D can be acute (short-term) or become a chronic (long-term) infection. Co-infection with both the hepatitis B virus and the hepatitis D virus (superinfection) is the most severe form of chronic hepatitis and can rapidly lead to the development of hepatocellular carcinoma (liver cancer; HCC) or death. Hepatitis D is transmitted by blood or body fluids through sexual contact, the shared use of contaminated needles, or infected blood transfusions.
What are the symptoms of Hepatitis D?
Symptoms of an acute hepatitis D infection may include weakness, fatigue, lack of appetite, nausea and vomiting, right upper abdominal pain over the liver, dark urine, pale stool, and jaundice (yellowing of eyes and skin). Individuals with a chronic hepatitis D infection may have little or no symptoms for years until developing cirrhosis (scarring liver disease) when they may experience weakness, fatigue, weight loss, abdominal swelling, ankle swelling (edema), itching, and jaundice. Chronic hepatitis D infection may cause severe complications, such hepatocellular carcinoma (liver cancer) and death.
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What are the current treatments for Hepatitis D?
There is currently no treatment for acute hepatitis D infection. Chronic hepatitis D infection may be treated with pegylated interferon alpha for at least 48 weeks or antiviral drugs, such as entecavir. Hepatitis D infection can be prevented with the hepatitis B vaccine.
Who are the top Hepatitis D Local Doctors?
Heiner H. Wedemeyer
Elite in Hepatitis D
Heiner H. Wedemeyer
Hepatology
Elite in Hepatitis D
Heiner H. Wedemeyer
Hepatology
Carl Neuberg Str. 1, 
Hannover, NI, DE 

Heiner Wedemeyer is a Hepatologist in Hannover, Germany. Mr. Wedemeyer is rated as an Elite expert by MediFind in the treatment of Hepatitis D. His top areas of expertise are Hepatitis D, Hepatitis, Hepatitis C, Liver Transplant, and Hepato-Pancreato-Biliary Surgery.

Cihan Yurdaydin
Elite in Hepatitis D
Cihan Yurdaydin
Elite in Hepatitis D
Cihan Yurdaydin
Istanbul, TR 

Cihan Yurdaydin practices in Istanbul, Turkey. Mr. Yurdaydin is rated as an Elite expert by MediFind in the treatment of Hepatitis D. His top areas of expertise are Hepatitis D, Hepatitis, Hepatitis B, Cirrhosis, and Liver Transplant.

 
 
 
 
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Ramazan Idilman
Elite in Hepatitis D
Ramazan Idilman
Elite in Hepatitis D
Ramazan Idilman
Ankara, TR 

Ramazan Idilman practices in Ankara, Turkey. Mr. Idilman is rated as an Elite expert by MediFind in the treatment of Hepatitis D. His top areas of expertise are Hepatitis D, Hepatitis, Hepatitis B, Non-Alcoholic Fatty Liver Disease, and Liver Transplant.

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What are the latest Hepatitis D Clinical Trials?
Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta
Phase 1/2 Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta
Enrollment Status: Recruiting
Publish Date: October 08, 2025
Intervention Type: Drug
Study Phase: Phase 1/Phase 2

Summary: The goals of this clinical study are to first learn more about safety and dosing of the study drug GS-4321 in healthy participants. The study will then learn about the safety and effectiveness of GS-4321 in participants with chronic hepatitis delta (CHD). The primary objective of Phase 1 of this study is to evaluate the safety, tolerability and Pharmacokinetics (PK) of the escalating single doses ...

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Evaluation of Patients With Liver Disease
Evaluation of Patients With Liver Disease
Enrollment Status: Recruiting
Publish Date: October 02, 2025

Summary: The proposed study aims to evaluate, investigate, and follow-up patients suffering from acute and chronic liver disease. The study will focus on understanding diseases affecting the liver. Patients participating in the study will first undergo a routine check-up as an outpatient. They will be asked to provide blood and urine samples for laboratory testing and will undergo an ultrasound of the live...

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